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Active, not recruiting Phase 2 Interventional

Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease

ClinicalTrials.gov ID: NCT04198922

Public ClinicalTrials.gov record NCT04198922. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 4, 2026, 11:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Acalabrutinib for Chronic Graft-Versus-Host Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This phase II trial studies how well acalabrutinib works in treating patients with chronic graft versus host disease. Acalabrutinib may be an effective treatment for graft-versus-host disease caused by a stem cell transplant.

Study identification

NCT ID
NCT04198922
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Enrollment
51 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 11, 2020 (Actual)
Primary completion
Sep 29, 2025 (Actual)
Completion
Apr 30, 2027 (Estimated)
Last update posted
Nov 5, 2025

2020 – 2027

United States locations

U.S. sites
6
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
Moffitt Cancer Center Tampa Florida 33612 —
Roswell Park Comprehensive Cancer Center Buffalo New York 14203 —
The Ohio State University Wexner Medical Center Columbus Ohio 43210 —
Vanderbilt University Medical Center Nashville Tennessee 37212 —
The University of Texas MD Anderson Cancer Center Houston Texas 77030 —
Fred Hutch/University of Washington Cancer Consortium Seattle Washington 98109 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04198922, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 5, 2025 · Synced Oct 4, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04198922 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →