Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants
Public ClinicalTrials.gov record NCT04209946. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized Trial of Preterm Infants Receiving Caffeine and Less Invasive Surfactant Administration Compared to Caffeine and Early Continuous Positive Airway Pressure (CaLI Trial)
Study identification
- NCT ID
- NCT04209946
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Sharp HealthCare
- Other
- Enrollment
- 180 participants
Conditions and interventions
Interventions
- Continuous Positive Airway Pressure CPAP Procedure
- Less Invasive Surfactant Administration LISA Procedure
Procedure
Eligibility (public fields only)
- Age range
- 24 Weeks to 29 Weeks
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 21, 2020
- Primary completion
- May 7, 2023
- Completion
- Nov 9, 2025
- Last update posted
- Dec 17, 2025
2020 – 2025
United States locations
- U.S. sites
- 3
- U.S. states
- 1
- U.S. cities
- 3
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California, Irvine | Irvine | California | 92868 | — |
| Loma Linda Medical Center | Loma Linda | California | 92350 | — |
| Sharp Mary Birch Hospital for Women & Newborns | San Diego | California | 92123 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04209946, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 17, 2025 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04209946 live on ClinicalTrials.gov.