Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients
Public ClinicalTrials.gov record NCT04217551. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients - A Multicenter, Randomized, Adaptive Clinical Trial to Identify the Optimal Duration of Induced Hypothermia for Neuroprotection in Comatose Survivors of Cardiac Arrest
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.
Study identification
- NCT ID
- NCT04217551
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,158 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 18, 2020 (Actual)
- Primary completion
- Aug 25, 2025 (Actual)
- Completion
- Feb 1, 2026 (Actual)
- Last update posted
- Jul 15, 2026
2020 – 2026
United States locations
- U.S. sites
- 76
- U.S. states
- 31
- U.S. cities
- 60
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Hospital | Birmingham | Alabama | 35233 | — |
| Banner University Medical Center | Tucson | Arizona | 85719 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Ronald Regan UCLA Medical Center | Los Angeles | California | 90095 | — |
| UC Davis Medical Center | Sacramento | California | 95817 | — |
| UC San Diego Medical Center - Hillcrest | San Diego | California | 92103 | — |
| Zuckerberg San Francisco General Hospital | San Francisco | California | 94110 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| George Washington University Hospital | Washington D.C. | District of Columbia | 20037 | — |
| UF Health Shands Hospital | Gainesville | Florida | 32608 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| The Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Illinois-Chicago Hosptial | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| IU Health Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky Hospital | Lexington | Kentucky | 40536 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University of Michigan Hospital | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Macomb Hospital | Clinton Township | Michigan | 48038 | — |
| Detroit Receiving Hospital | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| DMC Sinai Grace Hospital | Detroit | Michigan | 48235 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| M Health Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Cooper University Hospital | Camden | New Jersey | 08103 | — |
| University of New Mexico | Albuquerque | New Mexico | 87106 | — |
| South Shore University Hospital | Bay Shore | New York | 11706 | — |
| NYU Langone Health - Tisch Hospital | New York | New York | 10016 | — |
| The Mount Sinai Hospital | New York | New York | 10029 | — |
| NYP Columbia University Medical Center | New York | New York | 10032 | — |
| Strong Memorial Hospital | Rochester | New York | 14642 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Duke University Hospital | Durham | North Carolina | 27710 | — |
| ECU Health Medical Center | Greenville | North Carolina | 27834 | — |
| Wake Forest Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati | Cincinnati | Ohio | 45220 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| OSU East Hospital | Columbus | Ohio | 43203 | — |
| OSU Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Mercy St. Vincent Medical Center | Toledo | Ohio | 43608 | — |
| Adventist Health | Portland | Oregon | 97216 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| UPMC Harrisburg | Harrisburg | Pennsylvania | 17101 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Guthrie Robert Packer Hospital | Sayre | Pennsylvania | 18840 | — |
| Parkland Hospital | Dallas | Texas | 75235 | — |
| Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22903 | — |
| VCU Medical Center | Richmond | Virginia | 23298 | — |
| Providence Regional Medical Center Everett | Everett | Washington | 98201 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04217551, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 15, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04217551 live on ClinicalTrials.gov.