Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
Public ClinicalTrials.gov record NCT04221542. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer
Study identification
- NCT ID
- NCT04221542
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 479 participants
Conditions and interventions
Conditions
Interventions
- AMG 509 Drug
- Abiraterone Drug
- Enzalutamide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 3, 2020
- Primary completion
- Mar 21, 2030
- Completion
- Mar 20, 2032
- Last update posted
- May 7, 2026
2020 – 2032
United States locations
- U.S. sites
- 25
- U.S. states
- 19
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope National Medical Center | Duarte | California | 91010 | Recruiting |
| Providence Saint Jude Medical Center | Fullerton | California | 92835 | Recruiting |
| University of California San Francisco | San Francisco | California | 94158 | Recruiting |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | Recruiting |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | Recruiting |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Indiana University | Indianapolis | Indiana | 46202 | Recruiting |
| MidAmerica Cancer Care | Merriam | Kansas | 66204 | Recruiting |
| Tulane Medical Center | New Orleans | Louisiana | 70112 | Completed |
| Washington University | St Louis | Missouri | 63110 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Duke University Medical Center Duke Cancer Center | Durham | North Carolina | 27710 | Recruiting |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27103 | Recruiting |
| Oncology Hematology Care Incorporated | Cincinnati | Ohio | 45242 | Recruiting |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | Recruiting |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Prisma Health Upstate | Greenville | South Carolina | 29605 | Completed |
| Sanford Oncology Clinic and Pharmacy | Sioux Falls | South Dakota | 57104 | Recruiting |
| United States Oncology Regulatory Affairs Corporate Office | Nashville | Tennessee | 37203 | Recruiting |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| US Oncology Research Investigational Products Center | Irving | Texas | 75063 | Recruiting |
| Intermountain Medical Center | Murray | Utah | 84107 | Recruiting |
| Virginia Cancer Specialists PC | Fairfax | Virginia | 22031 | Recruiting |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04221542, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04221542 live on ClinicalTrials.gov.