ClinicalTrials.gov record
A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies
ClinicalTrials.gov ID: NCT04227847
Public ClinicalTrials.gov record NCT04227847. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:14 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Study of SEA-CD70 in Myeloid Malignancies
Study identification
- NCT ID
- NCT04227847
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Seagen, a wholly owned subsidiary of Pfizer
- Industry
- Enrollment
- 178 participants
Conditions and interventions
Conditions
Interventions
- SEA-CD70 Drug
- Venetoclax Drug
- azacitidine Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 6, 2020
- Primary completion
- Jul 3, 2027
- Completion
- Jul 2, 2028
- Last update posted
- Apr 6, 2026
2020 – 2028
United States locations
- U.S. sites
- 49
- U.S. states
- 13
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Active, not recruiting |
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | Active, not recruiting |
| Dept. of Medicine, UAB ONeal Comprehensive Cancer Center | Birmingham | Alabama | 35294 | Active, not recruiting |
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Duarte | California | 91010 | Recruiting |
| IP Address: City of Hope Investigational Drug Services(IDS) | Duarte | California | 91010 | Recruiting |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | Recruiting |
| UCLA Hematology-Oncology Clinic | Los Angeles | California | 90095 | Recruiting |
| Colorado Blood Cancer Institute, Lab | Denver | Colorado | 80218 | Active, not recruiting |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | Active, not recruiting |
| Presbyterian/St. Luke's Medical Center | Denver | Colorado | 80218 | Active, not recruiting |
| The University of Kansas Cancer Center ,Investigational Drug Services | Fairway | Kansas | 66205 | Recruiting |
| The University of Kansas Clinical Research Center | Fairway | Kansas | 66205 | Recruiting |
| The University of Kansas Hospital | Kansas City | Kansas | 66160 | Recruiting |
| University of Kansas Hospital Cambridge North Tower A | Kansas City | Kansas | 66160 | Recruiting |
| University of Kansas Medical center Medical office building | Kansas City | Kansas | 66160 | Recruiting |
| University of Kansas Medical Center Research Institute | Kansas City | Kansas | 66160 | Recruiting |
| The University of Kansas Cancer Center - Overland Park | Overland Park | Kansas | 66210 | Recruiting |
| The University of Kansas Cancer Center - Indian Creek Campus | Overland Park | Kansas | 66211 | Recruiting |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205 | Recruiting |
| Norton Hospitals, Inc | Louisville | Kentucky | 40202 | Recruiting |
| Norton Cancer Institute, St. Matthews Campus, Attn. Becky Champion, PharmD | Louisville | Kentucky | 40207 | Recruiting |
| Norton Cancer Institute, St. Matthews Campus | Louisville | Kentucky | 40207 | Recruiting |
| Norton Women & Children's Hospital | Louisville | Kentucky | 40207 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| Dana Farber/Mass General Brigham Cancer Care, Inc | Boston | Massachusetts | 02215 | Recruiting |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | Recruiting |
| Karmanos Cancer Institute Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | Recruiting |
| The University of Kansas Cancer Center - Medical Oncology Clinic | Kansas City | Missouri | 64116 | Recruiting |
| The University of Kansas Cancer Center - Radiation Oncology Clinic | Kansas City | Missouri | 64116 | Recruiting |
| The University of Kansas Cancer Center -North | Kansas City | Missouri | 64154 | Recruiting |
| The University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri | 64064 | Recruiting |
| Columbia University Irving Medical Center | New York | New York | 10032 | Recruiting |
| CUIMC Research Pharmacy | New York | New York | 10032 | Recruiting |
| The New York and Presbyterian Hospital | New York | New York | 10032 | Recruiting |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
| The Ohio State University Wexner Medical Center/James Cancer Hospital | Columbus | Ohio | 43210 | Recruiting |
| Hollings Cancer Center | Charleston | South Carolina | 29425 | Recruiting |
| Medical University of South Carolina- Ashley River Tower | Charleston | South Carolina | 29425 | Recruiting |
| Medical University of South Carolina- Investigational Drug Services | Charleston | South Carolina | 29425 | Recruiting |
| Medical University of South Carolina- University Hospital | Charleston | South Carolina | 29425 | Recruiting |
| Baylor Research Institute | Dallas | Texas | 75204 | Recruiting |
| Baylor University Medical Center, Investigational Drug Services, Department of Pharmacy | Dallas | Texas | 75246 | Recruiting |
| Baylor University Medical Center | Dallas | Texas | 75246 | Recruiting |
| Houston Methodist Hospital | Houston | Texas | 77030 | Recruiting |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Active, not recruiting |
| Swedish Cancer Institute | Seattle | Washington | 98104 | Recruiting |
| Swedish Medical Center | Seattle | Washington | 98122 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04227847, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 6, 2026 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04227847 live on ClinicalTrials.gov.