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Recruiting No phase listed Observational Accepts healthy volunteers

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

ClinicalTrials.gov ID: NCT04278404

Public ClinicalTrials.gov record NCT04278404. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 7, 2026, 9:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs

Study identification

NCT ID
NCT04278404
Recruitment status
Recruiting
Study type
Observational
Phase
Not listed
Lead sponsor
Duke University
Other
Enrollment
5,000 participants

Conditions and interventions

Interventions

  • The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: Drug

Drug

Eligibility (public fields only)

Age range
0 Years to 20 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 4, 2020
Primary completion
Feb 28, 2027
Completion
Jun 30, 2027
Last update posted
Apr 5, 2026

2020 – 2027

United States locations

U.S. sites
48
U.S. states
35
U.S. cities
43
Facility City State ZIP Site status
Phoenix Children's Hospital Phoenix Arizona 85016 Completed
Arkansas Children's Hospital Research Institute Little Rock Arkansas 72202 Recruiting
University of California, Los Angeles Medical Center Los Angeles California 90095 Recruiting
Lucile Packard Children's Hospital Palo Alto California 94304 Recruiting
Colorado University Denver Aurora Colorado 80045 Recruiting
The Children's Hospital Colorado Aurora Colorado 80045 Completed
Alfred I. DuPont Hospital for Children Wilmington Delaware 19803 Completed
University of Florida Jacksonville Shands Medical Center Jacksonville Florida 32209 Recruiting
Kapiolani Womens and Childrens Medical Center Honolulu Hawaii 96826 Recruiting
Ann and Robert H. Lurie Childrens Hospital of Chicago Chicago Illinois 60611 Completed
Ann and Robert H. Lurie Childrens Hospital of Chicago Chicago Illinois 60614 Recruiting
Riley Hospital for Children at Indiana University Indianapolis Indiana 46202 Recruiting
University of Iowa Stead Family Children's Hospital Iowa City Iowa 52242 Completed
University of Kansas Medical Center-JG Kidney Institute Kansas City Kansas 66160 Completed
University of Louisville Norton Childrens Hospital Louisville Kentucky 40202 Recruiting
Tulane University Health Science Center New Orleans Louisiana 70112 Completed
Ochsner Baptist Clinical Trials Unit New Orleans Louisiana 70115 Recruiting
University of Maryland Medical Center Baltimore Maryland 21201 Completed
Boston Children's Hospital Boston Massachusetts 02115 Completed
Massachusetts General Hospital Lexington Massachusetts 02421 Completed
University of Minnesota Minneapolis Minnesota 55455 Completed
University of Mississippi Medical Center Jackson Mississippi 39216 Recruiting
Mississippi Center for Advanced Medicine Madison Mississippi 39110 Completed
Children's Mercy Hospital Kansas City Missouri 64108 Completed
University of Nebraska Medical Center Omaha Nebraska 68114 Recruiting
Dartmouth-Hitchcock Medical Center Lebanon New Hampshire 03756 Completed
University of New Mexico Health Science Center Albuquerque New Mexico 87131 Completed
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 Completed
Duke University Health System Durham North Carolina 27710 Recruiting
Cincinnati Childrens Hospital Medical Center Cincinnati Ohio 45229 Recruiting
Board of Regents of the University of Oklahoma Oklahoma City Oklahoma 73104 Recruiting
Oregon Health and Science University Portland Oregon 97239 Recruiting
Pennsylvania State University--Hershey Children's Hospital Hershey Pennsylvania 17033 Completed
Rhode Island Hospital Providence Rhode Island 02903 Completed
Medical University of South Carolina Children's Hospital Charleston South Carolina 29425 Recruiting
University of South Carolina Columbia South Carolina 29208 Completed
Avera McKennan Hospital & University Medical Center Sioux Falls South Dakota 57108 Completed
Monroe Carell Jr. Children's Hospital at Vanderbilt Nashville Tennessee 37232 Recruiting
Dell Children's Medical Center of Central Texas Austin Texas 78723 Recruiting
University of Texas-Southwestern Medical Center Dallas Dallas Texas 75390 Active, not recruiting
University of Texas--Memorial Hermann Texas Medical Center Houston Texas 77030 Completed
The Womens Hospital of Texas Houston Texas 77054 Recruiting
University of Utah Salt Lake City Utah 84113 Recruiting
Seattle Children's Hospital Seattle Washington 98105 Recruiting
West Virginia University Hospital Morgantown West Virginia 26506 Active, not recruiting
University of Wisconsin Madison Wisconsin 53705 Recruiting
University Wisconsin Madison Madison Wisconsin 53705 Completed
Medical College of Wisconsin Milwaukee Wisconsin 53226 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04278404, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 5, 2026 · Synced May 7, 2026

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The complete protocol, eligibility criteria, and contact information for NCT04278404 live on ClinicalTrials.gov.

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