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Completed Phase 1 Interventional

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Adolescents and Adults With Chronic Plaque Psoriasis

ClinicalTrials.gov ID: NCT04279119

Public ClinicalTrials.gov record NCT04279119. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 28, 2026, 2:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open Label, Phase 1, Maximal Usage Pharmacokinetics and Safety Study of ARQ-151 Cream 0.3% Administered QD in Adolescent and Adult Subjects With Chronic Plaque Psoriasis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a phase 1, open label, single arm study in which ARQ-151 cream 0.3% is applied QD for 2 weeks to adolescent subjects with chronic plaque psoriasis involving at least 10% body surface area (BSA) and adult subjects with chronic plaque psoriasis involving at least 20% BSA (excluding scalp). The objectives of this study are to evaluate the exposure and characterize the plasma pharmacokinetic profile and to assess the safety and tolerability of ARQ-151 cream 0.3% administered once daily for 2 weeks to adolescent and adult subjects with chronic plaque psoriasis.

Study identification

NCT ID
NCT04279119
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Arcutis Biotherapeutics, Inc.
Industry
Enrollment
26 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 9, 2020
Primary completion
Mar 24, 2021
Completion
Mar 24, 2021
Last update posted
Aug 2, 2022

2020 – 2021

United States locations

U.S. sites
12
U.S. states
7
U.S. cities
12
Facility City State ZIP Site status
Arcutis Clinical Site 09 Rogers Arkansas 72758 —
Arcutis Clinical Site 11 Fountain Valley California 92708 —
Arcutis Clinical Site 07 Coral Gables Florida 33134 —
Arcutis Clinical Site 03 Doral Florida 33122 —
Arcutis Clinical Site 06 Hialeah Florida 33016 —
Arcutis Clinical Site 12 Miami Florida 33144 —
Arcutis Clinical Site 04 Sanford Florida 32771 —
Arcutis Clinical Site 02 Plainfield Indiana 46168 —
Arcutis Clinical Site 01 Dublin Ohio 43016 —
Arcutis Clinical Site 10 Arlington Texas 76011 —
Arcutis Clinical Site 05 San Antonio Texas 78213 —
Arcutis Clinical Site 08 Richmond Virginia 23226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04279119, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 2, 2022 · Synced Sep 28, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04279119 live on ClinicalTrials.gov.

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