ClinicalTrials.gov record
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
ClinicalTrials.gov ID: NCT04302025
Public ClinicalTrials.gov record NCT04302025. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 8:10 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
NAUTIKA1: A Multicenter, Phase II, Neoadjuvant and Adjuvant Study of Multiple Therapies in Biomarker-selected Patients With Resectable Stages IB-III Non-small Cell Lung Cancer
Study identification
- NCT ID
- NCT04302025
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Genentech, Inc.
- Industry
- Enrollment
- 99 participants
Conditions and interventions
Conditions
Interventions
- Alectinib Drug
- Atezolizumab Drug
- Chemotherapy Drug
- Cobimetinib Drug
- Divarasib Drug
- Entrectinib Drug
- Pralsetinib Drug
- Resection Procedure
- SBRT Drug
- Vemurafenib Drug
Drug · Procedure
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 5, 2020
- Primary completion
- Nov 29, 2026
- Completion
- May 29, 2030
- Last update posted
- Apr 2, 2026
2020 – 2030
United States locations
- U.S. sites
- 38
- U.S. states
- 18
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | Withdrawn |
| City of Hope - Orange County Lennar Foundation Cancer Center | Irvine | California | 92618 | Withdrawn |
| USC Norris Cancer Center | Los Angeles | California | 90033 | Withdrawn |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | Withdrawn |
| University of California Los Angeles - Jonsson Comprehensive Cancer Center | Los Angeles | California | 90095 | Recruiting |
| The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange | Orange | California | 92868 | Recruiting |
| UC Davis Comprehensive Cancer Center | Sacramento | California | 95817 | Recruiting |
| UCSF Helen Diller Family CCC | San Francisco | California | 94158 | Withdrawn |
| University of Colorado - Anschutz Medical Campus (University of Colorado Health Sciences Center) | Aurora | Colorado | 80045 | Withdrawn |
| Yale Cancer Center | New Haven | Connecticut | 06511 | Recruiting |
| MedStar Georgetown University Hospital (Lombardi Comprehensive Cancer Center) | Washington D.C. | District of Columbia | 20007 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| Northwestern Medicine Cancer Center Kishwaukee | DeKalb | Illinois | 60115 | Recruiting |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | Recruiting |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | Recruiting |
| Boston Medical Center | Boston | Massachusetts | 02118 | Withdrawn |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Karmanos Cancer Institute - Farmington Hills/Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | Withdrawn |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Ellis Fischel Cancer Center | Columbia | Missouri | 65201 | Recruiting |
| Siteman Cancer Center - Washington University Medical Campus | St Louis | Missouri | 63108 | Recruiting |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | Recruiting |
| Laura and ISAAC Perlmutter Cancer Center at NYU Langone. | New York | New York | 10016 | Recruiting |
| Columbia University Medical Center | New York | New York | 10032 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44016 | Withdrawn |
| Ohio State University | Columbus | Ohio | 43210 | Recruiting |
| AHN Cancer Institute ? Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | Completed |
| Baptist Clinical Research Institute | Memphis | Tennessee | 38120 | Recruiting |
| Tennessee Oncology - Nashville | Nashville | Tennessee | 37203 | Withdrawn |
| Kelsey Seybold Clnic | Houston | Texas | 77025 | Withdrawn |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030-4008 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Withdrawn |
| Lumi Research | Kingwood | Texas | 77339 | Withdrawn |
| Virginia Cancer Specialists (Fairfax) - USOR | Fairfax | Virginia | 22031 | Recruiting |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | Withdrawn |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04302025, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04302025 live on ClinicalTrials.gov.