ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas

ClinicalTrials.gov ID: NCT04308590

Public ClinicalTrials.gov record NCT04308590. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 8:32 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Glucocorticoid Receptor Antagonism in the Treatment of Hypercortisolism in Patients With Cortisol-Secreting Adrenal Adenomas or Hyperplasia (GRADIENT): A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Relacorilant

Study identification

NCT ID
NCT04308590
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Corcept Therapeutics
Industry
Enrollment
137 participants

Conditions and interventions

Interventions

  • Placebo Other
  • Relacorilant Drug

Other · Drug

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 26, 2020
Primary completion
Sep 18, 2024
Completion
Sep 18, 2024
Last update posted
Sep 3, 2025

2020 – 2024

United States locations

U.S. sites
22
U.S. states
16
U.S. cities
22
Facility City State ZIP Site status
Site 27 Birmingham Alabama 35294
Site 17 Stanford California 94305
Site 53 Torrance California 90502
Site 07 Atlanta Georgia 30318
Site 16 Indianapolis Indiana 46202
Site 09 Metairie Louisiana 70006
Site 36 Baltimore Maryland 21287
Site 11 Fall River Massachusetts 02721
Site 33 Rochester Minnesota 55905
Site 06 Jackson Mississippi 39202
Site 54 Reno Nevada 89511
Site 10 Jamaica New York 11432
Site 44 New York New York 10021
Site 01 Wilmington North Carolina 28401
Site 30 Cleveland Ohio 44195
Site 21 Columbus Ohio 43201-3209
Site 02 Summerville South Carolina 29485
Site 20 Dallas Texas 75390
Site 03 El Paso Texas 79935
Site 05 Fort Worth Texas 76132
Site 08 Houston Texas 77079
Site 15 Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04308590, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 3, 2025 · Synced May 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04308590 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →