An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab
Public ClinicalTrials.gov record NCT04353492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single-arm, Prospective, Multicentre, Open-label Study to Evaluate Ofatumumab Treatment Effectiveness and Patient-reported Outcomes (PRO) in Patients With Relapsing Multiple Sclerosis (RMS) Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod
Study identification
- NCT ID
- NCT04353492
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 562 participants
Conditions and interventions
Conditions
Interventions
- Ofatumumab Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 60 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 13, 2020
- Primary completion
- Oct 8, 2024
- Completion
- Mar 10, 2025
- Last update posted
- Apr 8, 2026
2020 – 2025
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Fullerton Neuro and Headache Ctr | Fullerton | California | 92835 | — |
| CU Anschutz Med Campus | Aurora | Colorado | 80045 | — |
| Christiana Care Health Services | Newark | Delaware | 19713 | — |
| Memorial Healthcare System | Hollywood | Florida | 33021 | — |
| Homestead Assoc In Research Inc | Homestead | Florida | 33033 | — |
| Neurology Associates PA | Maitland | Florida | 32751 | — |
| UM Department Of Neurology | Miami | Florida | 33136 | — |
| Negroski Neurology | Sarasota | Florida | 34233 | — |
| Axiom Clinical Research of Florida | Tampa | Florida | 33609 | — |
| University Of South Florida | Tampa | Florida | 33612 | — |
| Premiere Research Institute | West Palm Beach | Florida | 33407 | — |
| Atlanta Neuroscience Institute | Atlanta | Georgia | 30327 | — |
| Georgia Neurology and Sleep Medicine Assoc | Suwanee | Georgia | 30024 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Cleveland Clinic Foundation | Las Vegas | Nevada | 89106 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131-0001 | — |
| Five Towns Neuroscience Research | Woodmere | New York | 11598 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Columbus Neuroscience | Westerville | Ohio | 43082 | — |
| Multiple Sclerosis Center of Excellence of OMRF | Oklahoma City | Oklahoma | 73104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107-5098 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Saturn Research Solutions LLC | Plano | Texas | 75024 | — |
| INOVA Medical Group | Fairfax | Virginia | 22030 | — |
| Ascension St Francis Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 98 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04353492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 8, 2026 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04353492 live on ClinicalTrials.gov.