Passive Immunity Trial for Our Nation to Treat COVID-19 in Hospitalized Adults
Public ClinicalTrials.gov record NCT04362176. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Passive Immunity Trial for Our Nation (PassItOn)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to test the safety and efficacy of convalescent donor plasma to treat COVID-19 in hospitalized adults in a randomized, placebo-controlled setting. The effect of convalescent plasma will be compared to placebo on clinical outcomes, measured using the COVID-19 7-point Ordinal Clinical Progression Outcomes Scale at Day 15, among adults with COVID-19 requiring hospitalization.
Study identification
- NCT ID
- NCT04362176
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 974 participants
Conditions and interventions
Conditions
Interventions
- pathogen reduced SARS-CoV-2 convalescent plasma Biological
- Placebo Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 24, 2020 (Actual)
- Primary completion
- Jul 6, 2021 (Actual)
- Completion
- Aug 6, 2021 (Actual)
- Last update posted
- Nov 3, 2022
2020 – 2021
United States locations
- U.S. sites
- 26
- U.S. states
- 19
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Scripps Health | La Jolla | California | 92037 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| MedStar Health Research Institute/MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| The University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Our Lady of the Lake Regional Medical Center | Baton Rouge | Louisiana | 70808 | — |
| University of Maryland, Baltimore (University of Maryland Medical Center) | Baltimore | Maryland | 21201 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Newton-Wellelsey Hospital | Newton | Massachusetts | 012462 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| University of New Mexico Health Sciences Center | Albuquerque | New Mexico | 87131 | — |
| University at Buffalo/Buffalo General Medical Center | Buffalo | New York | 14203 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| Cleveland Clinic Ohio | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center and James Cancer Hospital | Columbus | Ohio | 43210 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37203 | — |
| Meharry Medical College | Nashville | Tennessee | 37208 | — |
| Utah Valley Hospital | Provo | Utah | 84604 | — |
| University of Utah Health | Salt Lake City | Utah | 84132 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| University of Washington | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04362176, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 3, 2022 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04362176 live on ClinicalTrials.gov.