Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)
Public ClinicalTrials.gov record NCT04365374. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized Controlled Trial of Post-Surgical Stereotactic Radiotherapy (SRT) Versus Surgically Targeted Radiation Therapy (STaRT) With Gamma Tile for Treatment of Newly Diagnosed Metastatic Brain Tumors.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial will be a randomized controlled study comparing the efficacy and safety of intraoperative radiation therapy using GammaTilesTM (GT) versus SRT 3-4 weeks following metastatic tumor resection which is the current standard of care.
Study identification
- NCT ID
- NCT04365374
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 230 participants
Conditions and interventions
Conditions
Interventions
- Gamma Tile-Surgically Targeted Radiation Therapy (STaRT) Device
- Stereotactic Radiation Therapy Radiation
Device · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 6, 2021 (Actual)
- Primary completion
- Aug 30, 2029 (Estimated)
- Completion
- Aug 30, 2029 (Estimated)
- Last update posted
- Oct 7, 2025
2021 – 2029
United States locations
- U.S. sites
- 37
- U.S. states
- 21
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HonorHeath Scottsdale Osborn Medical Center | Phoenix | Arizona | 85027 | — |
| University of Arkansas Medical Center | Little Rock | Arkansas | 72205 | — |
| Ascension St. Vincent's- Riverside | Jacksonville | Florida | 32204 | — |
| Baptist MD Anderson Cancer Center- Jacksonville | Jacksonville | Florida | 32207 | — |
| HCA Florida First Coast Neurology- Orange Park | Orange Park | Florida | 32073 | — |
| Advent health Orlando | Orlando | Florida | 32804 | — |
| Orlando Health | Orlando | Florida | 32806 | — |
| Florida Health Sciences Center, Inc. d/b/a Tampa General Hospital | Tampa | Florida | 33606 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322 | — |
| RUSH University | Chicago | Illinois | 60607 | — |
| Indiana University, IU Health Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| The University Of Kansas Cancer Center | Kansas City | Kansas | 66016 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Henry Ford Health | Detroit | Michigan | 48202 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| University Of Minnesota | Minneapolis | Minnesota | 55414 | — |
| Ellis Fischel Cancer Center at University of Missouri | Columbia | Missouri | 65212 | — |
| SSM Health Saint Louis University Hospital | St Louis | Missouri | 63110 | — |
| Dartmouth-Hitchcock | Lebanon | New Hampshire | 03766 | — |
| HMH Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Memorial Sloan Kettering | New York | New York | 10065 | — |
| Westchester Medical Center | Westchester | New York | 10595 | — |
| University of North Carolina Health | Chapel Hill | North Carolina | 27599 | — |
| ECU Health | Greenville | North Carolina | 27834 | — |
| Mayfield Brain and Spine | Cincinnati | Ohio | 45209 | — |
| Allegheny Health Network | Pittsburgh | Pennsylvania | 15212 | — |
| Brown University Health | Providence | Rhode Island | 02906 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| UT Southwestern Simmons Cancer Center | Dallas | Texas | 75235 | — |
| Baylor St. Luke's Medical Center | Baylor College of Medicine | Houston | Texas | 77030 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| The University of Texas M. D. Anderson Cancer Center | Houston | Texas | 77030 | — |
| UT Health San Antonio | San Antonio | Texas | 78249 | — |
| SCRI with Texas Oncology | The Woodlands | Texas | 77380 | — |
| Virginia Mason | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04365374, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 7, 2025 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04365374 live on ClinicalTrials.gov.