Study of Oral Ibrutinib Capsules to Assess Respiratory Failure in Adult Participants With Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Pulmonary Injury
Public ClinicalTrials.gov record NCT04375397. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
IbrutiNib in SARS CoV-2 Induced Pulmonary Injury and Respiratory Failure (iNSPIRE)
Study identification
- NCT ID
- NCT04375397
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 46 participants
Conditions and interventions
Conditions
Interventions
- Ibrutinib Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 5, 2020
- Primary completion
- May 9, 2021
- Completion
- Jun 7, 2021
- Last update posted
- May 31, 2022
2020 – 2021
United States locations
- U.S. sites
- 9
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford University School of Med /ID# 221954 | Stanford | California | 94305-2200 | — |
| Medstar Washington Hospital Center /ID# 221886 | Washington D.C. | District of Columbia | 20010-3017 | — |
| Duplicate_GW Medical Faculty Associates /ID# 222023 | Washington D.C. | District of Columbia | 20037 | — |
| Midway Immunology and Research /ID# 222004 | Ft. Pierce | Florida | 34982 | — |
| University of Miami /ID# 223227 | Miami | Florida | 33136 | — |
| Triple O Research Institute /ID# 222944 | West Palm Beach | Florida | 33407-3100 | — |
| Brigham & Women's Hospital /ID# 221847 | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center /ID# 222994 | Boston | Massachusetts | 02215-5400 | — |
| Intermountain Healthcare /ID# 221955 | Salt Lake City | Utah | 84103 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04375397, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 31, 2022 · Synced May 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04375397 live on ClinicalTrials.gov.