ClinicalTrials.gov record
A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease
ClinicalTrials.gov ID: NCT04387448
Public ClinicalTrials.gov record NCT04387448. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 19, 2026, 10:59 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease
Study identification
- NCT ID
- NCT04387448
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Goldfinch Bio, Inc.
- Industry
- Enrollment
- 96 participants
Conditions and interventions
Conditions
Interventions
- GFB-887 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 27, 2020
- Primary completion
- Oct 31, 2022
- Completion
- Oct 31, 2022
- Last update posted
- Nov 14, 2022
2020 – 2022
United States locations
- U.S. sites
- 74
- U.S. states
- 31
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35392 | — |
| Aventiv Research - Phoenix | Mesa | Arizona | 85210-6041 | — |
| Arizona Kidney Disease & Hypertension Centers (AKDHC) | Scottsdale | Arizona | 85258 | — |
| Academic Medical Research Institute (AMRI) | Glendale | California | 90022 | — |
| Amicis Research Center | Granada Hills | California | 91344 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Amicis Research Center | Northridge | California | 91324 | — |
| Valley Renal Medical Group | Northridge | California | 91324 | — |
| Respire Research - Palm Springs | Palm Springs | California | 92262 | — |
| North American Research Institute | San Dimas | California | 91773 | — |
| Dr. Malvin Yan Inc. | South Gate | California | 90280 | — |
| Valiance Clinical Research - Tarzana | Tarzana | California | 91356 | — |
| Amicis Research Center | Vacaville | California | 95687 | — |
| DaVita Mojave Sage Dialysis | Victorville | California | 92395-8322 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Colorado Kidney Care (Denver Nephrology) | Denver | Colorado | 80230 | — |
| Western Nephrology - Westminster | Wheat Ridge | Colorado | 80033 | — |
| DaVita Hartford North | Hartford | Connecticut | 06112 | — |
| Nephrology Associationes, P.A. | Newark | Delaware | 19713 | — |
| Prohealth Research Center - Doral | Doral | Florida | 33166 | — |
| Clinical Site Partners Leesburg, LLC | Leesburg | Florida | 34748 | — |
| Premier Clinical Research Institute | Miami | Florida | 33122 | — |
| Kidney & Hypertension Specialists of Miami | Miami | Florida | 33150 | — |
| Avanza Medical Research Center | Pensacola | Florida | 32503 | — |
| Coastal Nephrology Associates Research Center, LLC | Port Charlotte | Florida | 33952 | — |
| Florida Premier Research Institute - Clay Street | Winter Park | Florida | 32789 | — |
| Masters of Clinical Research, Inc. | Augusta | Georgia | 30909 | — |
| Inova Clinical Trials and Research Center | Tyrone | Georgia | 30290 | — |
| Boise Kidney and Hypertension Institute | Meridian | Idaho | 83642 | — |
| Research by Design, LLC | Chicago | Illinois | 60643 | — |
| Adventist Health Partners | Hinsdale | Illinois | 60521 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| University of Iowa College of Public Health | Iowa City | Iowa | 52242 | — |
| My Kidney Center, LLC | Manhattan | Kansas | 66502 | — |
| Louisiana Kidney Update, LLC | Lafayette | Louisiana | 70506 | — |
| Louisiana State University Health Sciences Center - School of Medicine - New Orleans | New Orleans | Louisiana | 70112 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Renal and Transplant Associates of New England, PC | Springfield | Massachusetts | 01107 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Wayne State University School of Medicine | Detroit | Michigan | 48201 | — |
| St. Clair Nephrology | Roseville | Michigan | 48066 | — |
| DaVita Clinical Research | Edina | Minnesota | 55435 | — |
| University of Minnesota - Center for Pediatric Obesity Medicine | Minneapolis | Minnesota | 55414 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Nephrology & Hypertension Associates Ltd | Tupelo | Mississippi | 38801 | — |
| Clinical Research Consultants | Kansas City | Missouri | 64111 | — |
| DaVita Pelican Point Dialysis | Las Vegas | Nevada | 89129 | — |
| Sierra Nevada Nephrology Consultants | Reno | Nevada | 89511 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Eastern Nephrology Associates PLLC | New Bern | North Carolina | 28562 | — |
| Akron Nephrology Associates, Inc. | Akron | Ohio | 44302 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Northeast Clinical Research Center | Bethlehem | Pennsylvania | 18017 | — |
| Rhode Island Hospital | East Providence | Rhode Island | 02915 | — |
| South Carolina Nephrology and Hypertension | Orangeburg | South Carolina | 29118 | — |
| Southeast Renal Research Institute | Chattanooga | Tennessee | 37404 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Tech University Health Sciences Center - Amarillo | Amarillo | Texas | 79106 | — |
| Arlington Nephrology, PC | Arlington | Texas | 76015 | — |
| Conroe Willis Medical Research | Conroe | Texas | 77304 | — |
| Renal Disease Research Institute | Dallas | Texas | 75235 | — |
| El Paso Kidney Specialists, PA | El Paso | Texas | 79935 | — |
| Xpress Trials LLC | Houston | Texas | 77036 | — |
| Prolato Clinical Research Center | Houston | Texas | 77054 | — |
| North Texas Kidney Disease Association | Lewisville | Texas | 75057-6039 | — |
| Clinical Advancement Center, PLLC | San Antonio | Texas | 78212 | — |
| San Antonio Kidney Disease Center Physicians Group, PLLC | San Antonio | Texas | 78258 | — |
| Clear Lake Specialties | Webster | Texas | 77598 | — |
| Utah Kidney Research Institute | Salt Lake City | Utah | 84115 | — |
| Tidewater Kidney Specialists - Riverview | Norfolk | Virginia | 23502 | — |
| Providence Medical Research Center | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04387448, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 14, 2022 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04387448 live on ClinicalTrials.gov.