A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease
Public ClinicalTrials.gov record NCT04391894. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-masked, Multicenter Study to Evaluate the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study was planned to be conducted in 2 parts: Part 1 to determine the efficacy and safety of ECF843 vs vehicle, followed by Part 2 with additional exploratory assessments of ECF843 vs Vehicle. Both parts of the study included a double-masked study design, with randomization stratified for subjects with Sjogren's Syndrome.
Study identification
- NCT ID
- NCT04391894
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 718 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 6, 2020 (Actual)
- Primary completion
- May 13, 2021 (Actual)
- Completion
- May 13, 2021 (Actual)
- Last update posted
- Jan 28, 2025
2020 – 2021
United States locations
- U.S. sites
- 52
- U.S. states
- 19
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Eye Center | Chandler | Arizona | 85224 | — |
| Carrot Eye Center | Mesa | Arizona | 85202 | — |
| Phoenix Eye Care and Dry Eye Ctr | Phoenix | Arizona | 85032 | — |
| Milton Hom OD | Azusa | California | 91702 | — |
| Orange County Opthamology Med Grp | Garden Grove | California | 92843 | — |
| Dr Kent Small | Glendale | California | 91203 | — |
| Global Research Management | Glendale | California | 91205 | — |
| United Medical Research Institute | Inglewood | California | 90301 | — |
| Harvard Eye Associates | Laguna Hills | California | 92653 | — |
| North Valley Eye Medical Group | Mission Hills | California | 91345 | — |
| The Eye Research Foundation | Newport Beach | California | 92663 | — |
| North Bay Eye Associates Inc | Petaluma | California | 94954 | — |
| Martel Eye Medical Group | Rancho Cordova | California | 95670 | — |
| Sierra Clin Trials Rsch Org | Santa Ana | California | 92705 | — |
| Vision Institute | Colorado Springs | Colorado | 80907 | — |
| Advanced Research LLC | Deerfield Beach | Florida | 33064 | — |
| Pinnacle Research Institute | Fort Lauderdale | Florida | 33309 | — |
| Eye Associates Of Fort Myers | Fort Myers | Florida | 33901 | — |
| Lee Shettle Eye & Hearing | Largo | Florida | 33773 | — |
| Mid Florida Eye Center Pa | Mt. Dora | Florida | 32757 | — |
| Kannarr Eye Care | Pittsburg | Kansas | 66762 | — |
| The Eye Care Institute | Louisville | Kentucky | 40206 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Silverstein Eye Centers | Kansas City | Missouri | 64133 | — |
| Moyes Eye Center | Kansas City | Missouri | 64154 | — |
| Tekwani Vision Center | St Louis | Missouri | 63128 | — |
| Comprehensive Eye Care Limited | Washington | Missouri | 63090 | — |
| NV Eye Surgery | Henderson | Nevada | 89052 | — |
| AdvanceMed Clinical Research | Las Vegas | Nevada | 89123 | — |
| Northern New Jersey Eye Institut PA | South Orange | New Jersey | 07079 | — |
| Cornerstone Eye Care | High Point | North Carolina | 27262 | — |
| Eye Care Assoc of Greater Cincinnati Inc | Cincinnati | Ohio | 45236 | — |
| Abrams Eye Center | Cleveland | Ohio | 44115 | — |
| Apex Eye Clinical Reserach | Mason | Ohio | 45040 | — |
| Scott Christie Eye Care Associates | Cranberry Township | Pennsylvania | 16066 | — |
| Bucci Laser Vision Institute | Wilkes-Barre Township | Pennsylvania | 18702 | — |
| Vance Thompson Vision Hospital | Sioux Falls | South Dakota | 57108 | — |
| Chattanooga Eye Institute | Chattanooga | Tennessee | 37411 | — |
| University Eye Specialists | Maryville | Tennessee | 37803 | — |
| Total Eye Care PA | Memphis | Tennessee | 38119 | — |
| Toyos Clinic | Nashville | Tennessee | 37215 | — |
| Advancing Vision Research LLC | Smyrna | Tennessee | 37167 | — |
| Texan Eye P A | Austin | Texas | 78731 | — |
| Intouch Clinical Research Center | Houston | Texas | 77034 | — |
| Neuro Eye Clinical Trials Inc | Houston | Texas | 77074 | — |
| Revolution Research | Lakeway | Texas | 78738 | — |
| Parkhurst NuVision | San Antonio | Texas | 78229 | — |
| Stacy R Smith MD PC | Salt Lake City | Utah | 84117 | — |
| Southern Utah Medical Research | St. George | Utah | 84790 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Virginia Eye Consultants | Norfolk | Virginia | 23502 | — |
| Periman Eye Institute | Seattle | Washington | 98119 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04391894, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 28, 2025 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04391894 live on ClinicalTrials.gov.