ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

5-HTP and Creatine for Depression

ClinicalTrials.gov ID: NCT04395183

Public ClinicalTrials.gov record NCT04395183. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 12:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

31P-MRS and Resting State Functional Connectivity Analysis of the Effects of 5-hydroxytryptophan and Creatine for Antidepressant Augmentation in Patients With SSRI/SNRI-resistant Major Depressive Disorder

Study identification

NCT ID
NCT04395183
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
University of Utah
Other
Enrollment
43 participants

Conditions and interventions

Interventions

  • 5-Hydroxytryptophan 100 MG Drug
  • Creatine monohydrate Drug
  • Placebo Drug
  • placebo matched to 5-HTP Drug

Drug

Eligibility (public fields only)

Age range
25 Years to 40 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2021
Primary completion
Jul 31, 2023
Completion
Feb 29, 2024
Last update posted
Jul 22, 2024

2021 – 2024

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
University of Utah Department of Psychiatry Salt Lake City Utah 84108

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04395183, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 22, 2024 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04395183 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →