The Effect of Dupilumab on Lung Inflammation and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe Asthma
Public ClinicalTrials.gov record NCT04400318. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double Blind, Placebo Controlled Study to Evaluate the Effect of Dupilumab on Airway Inflammation Through Assessments of Lung Function, Mucus Plugging and Other Lung Imaging Parameters in Patients With Asthma
Study identification
- NCT ID
- NCT04400318
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 109 participants
Conditions and interventions
Conditions
Interventions
- Dupilumab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 19, 2020
- Primary completion
- Jun 25, 2023
- Completion
- Aug 20, 2023
- Last update posted
- Sep 8, 2025
2020 – 2023
United States locations
- U.S. sites
- 10
- U.S. states
- 7
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Allianz Research Institute Site Number : 8400020 | Westminster | California | 92683 | — |
| University of Kansas School of Medicine Site Number : 8400008 | Kansas City | Kansas | 66103 | — |
| University of Michigan Site Number : 8400002 | Ann Arbor | Michigan | 48109 | — |
| The Lung Research Center Site Number : 8400010 | Chesterfield | Missouri | 63017 | — |
| American Health Research Site Number : 8400005 | Charlotte | North Carolina | 28277 | — |
| Velocity Clinical Research, Medford Site Number : 8400014 | Medford | Oregon | 97504 | — |
| Medical University of South Carolina - Pulmonary & Critical Care Clinical Research Program Site Number : 8400009 | Charleston | South Carolina | 29425 | — |
| VitaLink Research-Greenville Site Number : 8400013 | Greenville | South Carolina | 29615 | — |
| VitaLink Research - Spartanburg Site Number : 8400011 | Spartanburg | South Carolina | 29303 | — |
| ~Spartanburg Medical Research Site Number : 8400004 | Spartanburg | South Carolina | 29303 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04400318, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 8, 2025 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04400318 live on ClinicalTrials.gov.