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Terminated Phase 3 Interventional Results available

A Study to Assess Pulsed Inhaled Nitric Oxide vs Placebo in Subjects With Mild or Moderate COVID-19

ClinicalTrials.gov ID: NCT04421508

Public ClinicalTrials.gov record NCT04421508. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 1:53 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Pulsed, Inhaled Nitric Oxide (iNO) Versus Placebo in Subjects With Mild or Moderate Coronavirus (COVID-19)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A randomized, double-blind, placebo-controlled study to assess the efficacy and safety of pulsed inhaled iNO compared to placebo in subjects with COVID-19.

Study identification

NCT ID
NCT04421508
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bellerophon Pulse Technologies
Industry
Enrollment
191 participants

Conditions and interventions

Interventions

Combination Product

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 12, 2020 (Actual)
Primary completion
Dec 28, 2020 (Actual)
Completion
Jan 22, 2021 (Actual)
Last update posted
Feb 21, 2023

2020 – 2021

United States locations

U.S. sites
17
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
Banner University Medical Center Phoenix Arizona 85006 —
Kaiser Permanente - Zion Medical Center San Diego California 92120 —
Kaiser Permanente - San Diego Medical Center San Diego California 92123 —
University of Miami Health System Miami Florida 33136 —
The Lung Research Center (St. Luke's) Chesterfield Missouri 63017 —
University of New Mexico Hospital Albuquerque New Mexico 87106 —
The Ohio State University Wexner Medical Center Columbus Ohio 43210 —
Mercy Health St. Vincent Medical Center Toledo Ohio 43608 —
Temple University Hospital Philadelphia Pennsylvania 19140 —
Houston Methodist Houston Texas 77030 —
INOVA Falls Church Virginia 22042 —
St. Francis Medical Center Richmond Virginia 23114 —
Memorial Regional Medical Center Richmond Virginia 23116 —
Chippenham Medical Center Richmond Virginia 23225 —
Pulmonary Associates of Richmond Richmond Virginia 23226 —
St. Mary's Hospital Richmond Virginia 23226 —
Johnston-Willis Hospital Richmond Virginia 23235 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04421508, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 21, 2023 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04421508 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →