ClinicalTrials.gov record
Completed Phase 1 Interventional Accepts healthy volunteers

Study of Recombinant Influenza Vaccine Containing Different H3 Antigens Without or With Adjuvant in Healthy Adult Subjects

ClinicalTrials.gov ID: NCT04451954

Public ClinicalTrials.gov record NCT04451954. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 8:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Safety and Immunogenicity of Quadrivalent Recombinant Influenza Vaccine Formulations Containing Different H3 Hemagglutinin Antigens Without or With Adjuvant in Healthy Adult Subjects

Study identification

NCT ID
NCT04451954
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Enrollment
210 participants

Conditions and interventions

Interventions

  • Quadrivalent RIV with 2018-2019 NH H3 strain Biological
  • Quadrivalent RIV with 2018-2019 NH H3 strain and adjuvant Biological
  • Quadrivalent RIV with H3 strain 1 Biological
  • Quadrivalent RIV with H3 strain 1 and adjuvant Biological
  • Quadrivalent RIV with H3 strain 2 Biological
  • Quadrivalent RIV with H3 strain 2 and adjuvant Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 1, 2020
Primary completion
Sep 19, 2021
Completion
Sep 19, 2021
Last update posted
Sep 16, 2025

2020 – 2021

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
Investigational Site Number 8400003 San Diego California 92108
Investigational Site Number 8400002 Melbourne Florida 32934
Investigational Site Number 8400004 Orlando Florida 32806
Investigational Site Number 8400001 Peoria Illinois 61614
Investigational Site Number 8400005 Rockville Maryland 20850

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04451954, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 16, 2025 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04451954 live on ClinicalTrials.gov.

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