ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)

ClinicalTrials.gov ID: NCT04456998

Public ClinicalTrials.gov record NCT04456998. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 3:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Clinical Study to Evaluate the Efficacy and Safety of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)

Study identification

NCT ID
NCT04456998
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.
Industry
Enrollment
86 participants

Conditions and interventions

Interventions

  • GB002 (seralutinib) Drug
  • Generic Dry Powder Inhaler Device
  • Placebo Drug

Drug · Device

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 11, 2020
Primary completion
Oct 16, 2022
Completion
Oct 31, 2022
Last update posted
Nov 6, 2023

2020 – 2022

United States locations

U.S. sites
36
U.S. states
21
U.S. cities
34
Facility City State ZIP Site status
Pulmonary Associates, PA Phoenix Arizona 85032
Dept of Veterans Affairs Greater Los Angeles Healthcare System Los Angeles California 90073
UC Davis Medical Center Sacramento California 95817
The University of California San Francisco San Francisco California 94143
Medical Corporation Santa Barbara California 93105
Stanford Healthcare Stanford California 94305
The Lundquist Institute of Biomedical Innovation at Harbor-UCLA Medical Center Torrance California 90502
Central Florida Pulmonary Group, PA Altamonte Springs Florida 32701
Mayo Clinic Jacksonville Jacksonville Florida 32224
Cleveland Clinic Florida Weston Florida 33331
The Emory Clinic Atlanta Georgia 30322
University of Iowa Hospitals & Clinics Iowa City Iowa 52242
University of Kansas Medical Center Kansas City Kansas 66160
Kentuckiana Pulmonary Research Center Louisville Kentucky 40202
Tufts Medical Center Boston Massachusetts 02111
Brigham and Women's Hospital Boston Massachusetts 02115
University of Michigan Ann Arbor Michigan 48109
University of Minnesota Minneapolis Minnesota 55455
Mayo Clinic Rochester Minnesota 55905
Washington University School of Medicine St Louis Missouri 63110
University of Nebraska Medical Center Omaha Nebraska 68198
University of New Mexico Health Sciences Center Albuquerque New Mexico 87131
NYU Langone Health New York New York 10016
New York Presbyterian Hospital - Weill Cornell Medicine New York New York 10065
University of Rochester Medical Center Rochester New York 14642
University of Cincinnati Medical Center Cincinnati Ohio 45219
Cleveland Clinic Foundation Cleveland Ohio 44124
The Ohio State University Wexner Medical Center Columbus Ohio 43210
INTEGRIS Baptist Medical Center, Inc. Oklahoma City Oklahoma 73112
Oregon Health & Science University Portland Oregon 97239
Perelman Center for Advanced Medicine Philadelphia Pennsylvania 19104
Allegheny General Hospital Pittsburgh Pennsylvania 15212
UT Southwestern Medical Center Dallas Texas 75390
Houston Methodist Hospital Houston Texas 77030
University of Utah Health Salt Lake City Utah 84132
Medical College of Wisconsin - Froedtert Hospital Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 27 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04456998, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 6, 2023 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04456998 live on ClinicalTrials.gov.

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