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Terminated Phase 1 Interventional

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

ClinicalTrials.gov ID: NCT04458259

Public ClinicalTrials.gov record NCT04458259. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 3:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 1, OPEN-LABEL, MULTI-CENTER, DOSE-FINDING, PHARMACOKINETIC, SAFETY AND TOLERABILITY STUDY OF PF 07265807 IN PARTICIPANTS WITH SELECTED ADVANCED OR METASTATIC SOLID TUMOR MALIGNANCIES

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A First-in-Human Pharmacokinetic, Safety, and Tolerability Study of PF-07265807 as Monotherapy and in Combination in Participants with Advanced or Metastatic Solid Tumors

Study identification

NCT ID
NCT04458259
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pfizer
Industry
Enrollment
88 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 24, 2020 (Actual)
Primary completion
Nov 15, 2024 (Actual)
Completion
Nov 15, 2024 (Actual)
Last update posted
Jun 4, 2026

2020 – 2024

United States locations

U.S. sites
25
U.S. states
8
U.S. cities
12
Facility City State ZIP Site status
Henry Eye Clinic Fayetteville Arkansas 72703 —
Highlands Oncology Group Fayetteville Arkansas 72703 —
Highlands Oncology Group Rogers Arkansas 72758 —
Highlands Oncology Group Springdale Arkansas 72762 —
UCI Chao Family Comprehensive Cancer Center Orange California 92868 —
Clinical & Translational Science Institute San Francisco California 94158 —
UCSF Helen Diller Family Comprehensive Cancer Center - Mission Hall San Francisco California 94158 —
UCSF Helen Diller Family Comprehensive Cancer Center San Francisco California 94158 —
Rocky Mountain Lions Eye Institute (RMLEI) Aurora Colorado 80045 —
University of Colorado Hospital - Anschutz Cancer Pavilion (ACP) Aurora Colorado 80045 —
University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP) Aurora Colorado 80045 —
University of Colorado Hospital - Anschutz Outpatient Pavilion (AOP) Aurora Colorado 80045 —
Community Health Network, Inc. Indianapolis Indiana 46219 —
Community Health Network, Inc. Indianapolis Indiana 46227 —
Community Health Network Cancer Center North Indianapolis Indiana 46250 —
Community Health Network, Inc. Indianapolis Indiana 46250 —
Community Health Network, Inc. Indianapolis Indiana 46256 —
Brigham & Women's Hospital Boston Massachusetts 02115 —
Dana Farber Cancer Institute Boston Massachusetts 02215 —
Dana-Farber Cancer Institute - Chestnut Hill Newton Massachusetts 02459 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
John Theurer Cancer Center at Hackensack University Medical Center Hackensack New Jersey 07601 —
Duke Eye Center Durham North Carolina 27705 —
Duke University Medical Center, lnvestigational Chemotherapy Service Durham North Carolina 27710 —
The University of Texas M. D. Anderson Cancer Center Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04458259, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 4, 2026 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04458259 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →