A Study of NGM621 in Participants With Geographic Atrophy
Public ClinicalTrials.gov record NCT04465955. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Multicenter, Randomized, Double-Masked, Sham-Controlled Study of the Safety and Efficacy of Intravitreal Injections of NGM621 in Subjects With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multi-center evaluation of NGM621 in a randomized, double-masked, sham-controlled study in participants with Geographic Atrophy secondary to Age-related Macular Degeneration.
Study identification
- NCT ID
- NCT04465955
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 320 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 22, 2020 (Actual)
- Primary completion
- Aug 16, 2022 (Actual)
- Completion
- Aug 16, 2022 (Actual)
- Last update posted
- Jul 1, 2025
2020 – 2022
United States locations
- U.S. sites
- 65
- U.S. states
- 25
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants | Phoenix | Arizona | 85020 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retina Vitreous Associates | Beverly Hills | California | 90211 | — |
| Retinal Diagnostic Center | Campbell | California | 95008 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Loma Linda University Health | Loma Linda | California | 92354 | — |
| University of California Los Angeles | Los Angeles | California | 90095 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Retina Institute of California | Palm Desert | California | 92260 | — |
| California Eye Specialists | Pasadena | California | 91107 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95841 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| Retina Consultants of Southern Colorado PC | Colorado Springs | Colorado | 80909 | — |
| Colorado Retina Associates PC | Golden | Colorado | 80401 | — |
| New England Retina Associates PC | Waterford | Connecticut | 06385 | — |
| Florida Eye Microsurgical Institute | Boynton Beach | Florida | 33426 | — |
| University of Miami | Coral Gables | Florida | 33146 | — |
| Specialty Retina Center (Coral Springs) | Coral Springs | Florida | 33067 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Southern Vitreoretinal Associates | Tallahassee | Florida | 32308 | — |
| Retina Vitreous Associates of Florida | Tampa | Florida | 33607 | — |
| Georgia Retina PC | Marietta | Georgia | 30060 | — |
| Gailey Eye Clinic - Bloomington | Bloomington | Illinois | 61704 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| University Retina and Macula Associates, PC | Lemont | Illinois | 60439 | — |
| Raj K. Maturi, MD, PC | Indianapolis | Indiana | 46290 | — |
| Retina Associates, PA | Shawnee Mission | Kansas | 66204 | — |
| Thompson Sjaarda, PA | Baltimore | Maryland | 21204 | — |
| Elman Retina Group PA | Baltimore | Maryland | 21237 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Associated Retina Consultants PC | Royal Oak | Michigan | 48073 | — |
| Associated Retina Consultants PC | Traverse City | Michigan | 49686 | — |
| Vitreoretinal Surgery PA | Minneapolis | Minnesota | 55435 | — |
| Deep Blue Retina Clinical Research | Southaven | Mississippi | 38671 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Long Island Vitreoretinal Consultants | Great Neck | New York | 11021 | — |
| Vitreous Retina Macula Consultants of NY | New York | New York | 10022 | — |
| Albany Troy Cataract & Laser Associates | Troy | New York | 12180 | — |
| Western Carolina Retinal Associates | Asheville | North Carolina | 18803 | — |
| Southeast Clinical Research | Charlotte | North Carolina | 28210 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| Sterling Research Group, Ltd. | Cincinnati | Ohio | 45219 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44122 | — |
| The Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Cascade Medical Research Institute | Springfield | Oregon | 97477 | — |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | — |
| Retinovitreous Associates | Philadelphia | Pennsylvania | 19107 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Southeastern Retina Associates | Knoxville | Tennessee | 37922 | — |
| Tennessee Retina | Nashville | Tennessee | 37203 | — |
| Texas Retina Associates | Arlington | Texas | 76012 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | — |
| Texas Retina Associates-Plano | Dallas | Texas | 75231 | — |
| Retina Consultants of Houston | Houston | Texas | 77030 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04465955, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2025 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04465955 live on ClinicalTrials.gov.