A Single Arm Study Evaluating the Efficacy, Safety and Tolerability of Ofatumumab in Patients With Relapsing Multiple Sclerosis
Public ClinicalTrials.gov record NCT04486716. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single-arm, Prospective, Multi-center Study to Explore Maintained Efficacy With Ofatumumab Therapy in Patients With Relapsing Multiple Sclerosis Who Discontinue Intravenously Delivered Anti-CD20 Monoclonal Antibody (aCD20 mAb) Therapy (OLIKOS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A single arm study evaluating the continued efficacy, safety and tolerability of ofatumumab in patients with relapsing multiple sclerosis who are transitioning from aCD20 mAb therapy
Study identification
- NCT ID
- NCT04486716
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 111 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 60 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 19, 2020 (Actual)
- Primary completion
- Nov 20, 2023 (Actual)
- Completion
- Oct 21, 2024 (Actual)
- Last update posted
- Jan 13, 2026
2020 – 2024
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Neurology Associates PC | Birmingham | Alabama | 35209 | — |
| Ctr for Neurology and Spine | Phoenix | Arizona | 85018 | — |
| Neuro Center | Pomona | California | 91767 | — |
| UC Health Neuroscience Ctr | Aurora | Colorado | 80045 | — |
| Infinity Clinical Research LLC | Hollywood | Florida | 33024 | — |
| AMO Corporation | Tallahassee | Florida | 32312 | — |
| University Of South Florida | Tampa | Florida | 33612 | — |
| International Neurorehab Institute | Lutherville | Maryland | 21093 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Cente | Boston | Massachusetts | 02215 | — |
| Neurology Center of New England PC | Foxborough | Massachusetts | 02035 | — |
| Dragonfly Research LLC | Wellesley | Massachusetts | 02481 | — |
| Cleveland Clinic Foundation | Las Vegas | Nevada | 89106 | — |
| Ms Ctr Of Northeastern Ny | Latham | New York | 12110 | — |
| Columbus Neuroscience | Westerville | Ohio | 43082 | — |
| Sibyl Wray MD Neurology PC | Knoxville | Tennessee | 37922 | — |
| Parkland Health and Hospital Systems | Dallas | Texas | 75325 | — |
| Central TX Neuro Consultants P A | Round Rock | Texas | 78681 | — |
| Swedish Neuroscience Institute | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04486716, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 13, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04486716 live on ClinicalTrials.gov.