A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

ClinicalTrials.gov ID: NCT04492722

Public ClinicalTrials.gov record NCT04492722. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 25, 2026, 11:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b Randomised, Double-Blind, Placebo-Controlled, Multi-Centre, Dose-Ranging Study of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to evaluate the dose-response efficacy, safety, and pharmacokinetics (PK) of AZD5718 in participants with proteinuric chronic kidney disease.

Study identification

NCT ID: NCT04492722
Recruitment status: Terminated
Study type: Interventional
Phase: Phase 2
Lead sponsor: AstraZeneca; Industry
Enrollment: 613 participants

Conditions and interventions

Conditions

Chronic Kidney Disease

Interventions

Drug

Eligibility (public fields only)

Age range: 18 Years to 130 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Oct 1, 2020 (Actual)
Primary completion: Sep 6, 2022 (Actual)
Completion: Sep 6, 2022 (Actual)
Last update posted: Dec 20, 2024

2020 – 2022

United States locations

U.S. sites: 22
U.S. states: 11
U.S. cities: 22

Facility	City	State	ZIP	Site status
Research Site	Canoga Park	California	91303	—
Research Site	La Mesa	California	91942	—
Research Site	San Carlos	California	94070	—
Research Site	San Francisco	California	94110	—
Research Site	Victorville	California	92392	—
Research Site	Denver	Colorado	80045	—
Research Site	Jacksonville	Florida	32216	—
Research Site	Winter Haven	Florida	33880	—
Research Site	Columbus	Georgia	31904	—
Research Site	Roseville	Michigan	48066	—
Research Site	Hazelwood	Missouri	63042	—
Research Site	Fresh Meadows	New York	11365	—
Research Site	Great Neck	New York	11021	—
Research Site	Jamaica	New York	11432	—
Research Site	Blue Ash	Ohio	45242	—
Research Site	East Providence	Rhode Island	02914	—
Research Site	Memphis	Tennessee	38104-2127	—
Research Site	Austin	Texas	78738	—
Research Site	Houston	Texas	77099	—
Research Site	Pearland	Texas	77584	—
Research Site	San Antonio	Texas	78215	—
Research Site	Schertz	Texas	78154	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 89 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04492722, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Dec 20, 2024 · Synced Oct 25, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04492722 live on ClinicalTrials.gov.

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