Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery
Public ClinicalTrials.gov record NCT04498117. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter Phase 3, Double-Blind, Placebo-Controlled Study Comparing Chemo-Immunotherapy (Paclitaxel-Carboplatin- Oregovomab) vs Chemotherapy (Paclitaxel-Carboplatin- Placebo) in Patients With Advanced Epithelial Ovarian, Fallopian Tube or Peritoneal Carcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemotherapy regimen (paclitaxel and carboplatin), for the treatment of subjects with newly diagnosed advanced ovarian cancer who have undergone optimal debulking.
Study identification
- NCT ID
- NCT04498117
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 615 participants
Conditions and interventions
Conditions
Interventions
- Oregovomab Biological
- Paclitaxel Drug
- Carboplatin Drug
- Placebo Biological
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 25, 2020 (Actual)
- Primary completion
- Dec 26, 2026 (Estimated)
- Completion
- Aug 26, 2028 (Estimated)
- Last update posted
- Apr 1, 2026
2020 – 2028
United States locations
- U.S. sites
- 81
- U.S. states
- 27
- U.S. cities
- 73
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Honor Health | Phoenix | Arizona | 85016 | — |
| The University of Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| John Muir Health Clinical Research Center | Concord | California | 94520 | — |
| Kaiser Permanente Southern California | Irvine | California | 92120 | — |
| Moores UC San Diego Cancer Center | La Jolla | California | 92093 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Epic Care | Pleasant Hill | California | 94523 | — |
| Kaiser Permanente Riverside Medical Center | Riverside | California | 95505 | — |
| University of California, Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Contra Costa Oncology | Walnut Creek | California | 94598 | — |
| John Muir Health Gynecologic Cancer Services | Walnut Creek | California | 94598 | — |
| University of Colorado Health | Aurora | Colorado | 80045 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030 | — |
| Smilow Cancer Hospital | New Haven | Connecticut | 06510 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| AdventHealth Orlando | Orlando | Florida | 32804 | — |
| Women's Cancer Florida/Women's Cancer Associates | St. Petersburg | Florida | 33701 | — |
| Lewis Cancer & Research Pavilion at St. Joseph's Candler | Savannah | Georgia | 31405 | — |
| The Queens Medical Center | Honolulu | Hawaii | 96813 | — |
| Kapiolani Medical Center for Women and Children/University of Hawaii | Honolulu | Hawaii | 96826 | — |
| Parkview Research Center | Fort Wayne | Indiana | 46845 | — |
| Women's Cancer Care/Mary Bird Perkins Cancer Center | Covington | Louisiana | 70433 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| MetroWest Medical Center | Farmington | Massachusetts | 01702 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| Tufts Medical Center Cancer Center in Stoneham | Stoneham | Massachusetts | 02180 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01605 | — |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | — |
| Sparrow Hospital | Lansing | Michigan | 48219 | — |
| Minnesota Oncology Hematology - Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Minnesota Oncology Hematology | Edina | Minnesota | 55435 | — |
| University of Minnesota Health - Maple Grove Clinic | Maple Grove | Minnesota | 55369 | — |
| Minnesota Oncology Hematology | Minneapolis | Minnesota | 55404 | — |
| Metro Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Frauenshuh Cancer Center | Saint Louis Park | Minnesota | 55426 | — |
| Minnesota Oncology Hematology | Saint Paul | Minnesota | 55102 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Portsmouth Regional Hospital | Portsmouth | New Hampshire | 03801 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| The Valley Hospital (Valley Health) | Paramus | New Jersey | 07450 | — |
| Womens Cancer Care Associates | Albany | New York | 12208 | — |
| Mount Sinai - PRIME | Lake Success | New York | 10019 | — |
| Mount Sinai The Blavatnik Family Chelsea Medical Center | New York | New York | 10011 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| Montefiore Medical Center PRIME | The Bronx | New York | 10461 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Duke Women's Cancer Care Raleigh | Raleigh | North Carolina | 27607 | — |
| SCC at UH Geauga Medical Center | Chardon | Ohio | 44024 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43026 | — |
| Grandview Medical Center/Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Cleveland Clinic Hillcrest Hospital | Mayfield Heights | Ohio | 44124 | — |
| UH Minoff Health Center - Seidman | Orange | Ohio | 44122 | — |
| SCC at St. John's Medical Center | Westlake | Ohio | 44145 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Oklahoma Cancer Specialist and Research Institution, LLC | Tulsa | Oklahoma | 74146 | — |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | — |
| Northwest Cancer Specialists, P.C.-Portland-Rose Quarter | Portland | Oregon | 97227 | — |
| Magee Women's Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Hillman Cancer Center at UPMC Passavant | Pittsburgh | Pennsylvania | 15237-9643 | — |
| Women & Infants Hospital of Rhode Island | Providence | Rhode Island | 02905 | — |
| Sanford Research/USD-Sioux Falls | Sioux Falls | South Dakota | 57104 | — |
| Texas Oncology, P.A. - Austin | Austin | Texas | 78731 | — |
| Texas Oncology, P.A. | Dallas | Texas | 75231 | — |
| Texas Oncology, P.A. - Fort Worth | Fort Worth | Texas | 76104 | — |
| Memorial Herman Hospital | Houston | Texas | 77030 | — |
| Texas Oncology San Antonio Medical Center | San Antonio | Texas | 78240 | — |
| University of Virginia Health Systems | Charlottesville | Virginia | 22903 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 21055 | — |
| Virginia Oncology Associates - Hampton | Norfolk | Virginia | 23502 | — |
| VCU Massey Cancer Center | Richmond | Virginia | 23298 | — |
| Carilion Clinic Gynecological Oncology | Roanoke | Virginia | 24106 | — |
| MultiCare Regional Cancer Center - Auburn | Auburn | Washington | 98001 | — |
| MultiCare Regional Cancer Center-Gig Harbor Medical Park | Gig Harbor | Washington | 98335 | — |
| MultiCare Institute for Research and Innovation | Puyallup | Washington | 98372 | — |
| MultiCare Regional Cancer Center - Tacoma | Tacoma | Washington | 98405 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 67 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04498117, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 1, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04498117 live on ClinicalTrials.gov.