ClinicalTrials.gov record
Active, not recruiting Phase 1Phase 2 Interventional

Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC

ClinicalTrials.gov ID: NCT04506567

Public ClinicalTrials.gov record NCT04506567. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 10:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I/II Dose-escalation Study of Fractionated and Multiple Dose 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer

Study identification

NCT ID
NCT04506567
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Weill Medical College of Cornell University
Other
Enrollment
60 participants

Conditions and interventions

Interventions

  • 68Ga-PSMA-HBED-CC injection Diagnostic Test
  • Fractionated dose of 225Ac-J591 Drug
  • Multiple single doses of 225Ac-J591 Drug

Diagnostic Test · Drug

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 17, 2020
Primary completion
May 31, 2025
Completion
May 31, 2026
Last update posted
Feb 16, 2026

2020 – 2026

United States locations

U.S. sites
2
U.S. states
1
U.S. cities
2
Facility City State ZIP Site status
Brooklyn Methodist Hospital - New York Presbyterian Brooklyn New York 11215
Weill Cornell Medicine New York New York 10065

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04506567, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 16, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04506567 live on ClinicalTrials.gov.

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