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Completed Phase 2 Interventional Results available

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

ClinicalTrials.gov ID: NCT04564027

Public ClinicalTrials.gov record NCT04564027. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 3:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Modular Phase 2a Multicentre Open-Label Study to Investigate DNA-damage Response Agents (or Combinations) in Patients With Advanced Cancer Whose Tumours Contain Molecular Alterations (PLANETTE)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study is investigating efficacy, safety and tolerability of DNA-damage Response Agents (or Combinations), in participants with advanced/metastatic solid malignancies whose tumours contain molecular alterations

Study identification

NCT ID
NCT04564027
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
54 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 130 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 1, 2020 (Actual)
Primary completion
Feb 18, 2025 (Actual)
Completion
Feb 18, 2025 (Actual)
Last update posted
Aug 29, 2025

2020 – 2025

United States locations

U.S. sites
12
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Research Site Duarte California 91010 —
Research Site Los Angeles California 90089 —
Research Site San Francisco California 94115 —
Research Site Tampa Florida 33612 —
Research Site Indianapolis Indiana 46202 —
Research Site Baltimore Maryland 21231 —
Research Site Ann Arbor Michigan 48109 —
Research Site Las Vegas Nevada 89119 —
Research Site New York New York 10065 —
Research Site Ephrata Pennsylvania 17522 —
Research Site Philadelphia Pennsylvania 19104 —
Research Site Myrtle Beach South Carolina 29572 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04564027, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 29, 2025 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04564027 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →