Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

ClinicalTrials.gov ID: NCT04567420

Public ClinicalTrials.gov record NCT04567420. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 7, 2026, 3:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Phase II Trial of Circulating Tumor DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A randomized, Phase II trial of circulating tumor DNA-guided second line Adjuvant therapy for high Residual risk, Estrogen Receptor positive, HER-2 negative breast cancer (DARE)

Study identification

NCT ID
NCT04567420
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Criterium, Inc.
Industry
Enrollment
70 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
Not listed
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 8, 2021
Primary completion
Dec 30, 2027
Completion
Dec 30, 2028
Last update posted
Jul 7, 2026

2021 – 2028

United States locations

U.S. sites
19
U.S. states
16
U.S. cities
18
Facility City State ZIP Site status
University of Arizona Cancer Center Tucson Arizona 85724
USC/Norris Comprehensive Cancer Center Los Angeles California 90033
Cedars-Sinai Medical Center Los Angeles California 90048
University of Colorado Cancer Center Aurora Colorado 80045
Intermountain Golden Colorado 80401
Yale Cancer Center New Haven Connecticut 06510
Winship Cancer Institute of Emory University Atlanta Georgia 30322
Louisiana State University Health Sciences Center- New Orleans New Orleans Louisiana 70112
Cancer Partners of Nebraska Lincoln Nebraska 68516
New Mexico Cancer Care Alliance Albuquerque New Mexico 87131
Icahn School of Medicine at Mount Sinai New York New York 10029
Stony Brook University Cancer Center Stony Brook New York 11794
The Ohio State University Wexner Medical Center James Cancer Hospital Columbus Ohio 43210
Stephenson Cancer Center Oklahoma City Oklahoma 73104
Oregon Health and Science University Portland Oregon 97239
PRiSMs Group Laredo Texas 78041
Virginia Cancer Institute Richmond Virginia 23229
Swedish Cancer Institute Seattle Washington 98104
University of Wisconsin Clinical Science Center Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04567420, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 7, 2026 · Synced Sep 7, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04567420 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →