A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome
Public ClinicalTrials.gov record NCT04572243. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study With Open-Label Extension Phase of Lorcaserin as Adjunctive Treatment in Subjects With Dravet Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of the study is to demonstrate that lorcaserin has superior efficacy compared to placebo on percent change in frequency of convulsive seizures per 28 days in participants with Dravet syndrome.
Study identification
- NCT ID
- NCT04572243
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 22 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 23, 2020 (Actual)
- Primary completion
- Aug 15, 2024 (Actual)
- Completion
- Aug 15, 2024 (Actual)
- Last update posted
- Oct 8, 2025
2020 – 2024
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's of Alabama / University of Alabama at Birmingham | Birmingham | Alabama | 35226 | — |
| University of California Los Angeles (UCLA) | Los Angeles | California | 90095 | — |
| UCSD Rady's Children's Hosptial | San Diego | California | 92123 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Northwest Florida Clinical Research Group | Gulf Breeze | Florida | 32561 | — |
| Joe DiMaggio Children's Hospital | Hollywood | Florida | 33021 | — |
| Miami Children's Hospital - Nicklaus Children's Hospital | Miami | Florida | 33155 | — |
| Pediatric Neurology, P.A. | Winter Park | Florida | 32789 | — |
| Rare Disease Research Center Pediatrics, LLC | Atlanta | Georgia | 30318 | — |
| Mid-Atlantic Epilepsy and Sleep Center - Bethesda | Bethesda | Maryland | 20817 | — |
| Spectrum Health/ Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| University of Missouri, Department of Child Health, Division of Neurology | Columbia | Missouri | 65201 | — |
| Institute of Neurology and Neurosurgery at Saint Barnabas | Livingston | New Jersey | 07039 | — |
| Northwell Health - Neuroscience Institute at Great Neck | New Hyde Park | New York | 10075 | — |
| NYU Langone Comprehensive Epilepsy Center | New York | New York | 10016 | — |
| New York Medical College | New York | New York | 10019-1147 | — |
| NorthWell Health - Lennox Hill Hospital | New York | New York | 11021 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27599-7025 | — |
| Duke University Hospital Center | Durham | North Carolina | 27710 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Seattle Children's Hospital | Seattle | Washington | 98105 | — |
| MultiCare Institute for Research & Innovation | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04572243, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2025 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04572243 live on ClinicalTrials.gov.