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Recruiting Not applicable Interventional

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

ClinicalTrials.gov ID: NCT04592445

Public ClinicalTrials.gov record NCT04592445. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:39 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction: Randomized Controlled Feasibility Trial - The Rebalance HF Study

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this clinical study is to evaluate the safety and early effectiveness of a catheter-based procedure that treats a nerve called the right greater splanchnic nerve. The study includes people who have heart failure with preserved ejection fraction (HFpEF). The goal is to learn whether this procedure, performed using the Satera Ablation System, may help improve symptoms and to better understand which patients may benefit most from this treatment in the future.

Study identification

NCT ID
NCT04592445
Recruitment status
Recruiting
Study type
Interventional
Phase
Not applicable
Lead sponsor
Axon Therapies, Inc.
Industry
Enrollment
150 participants

Conditions and interventions

Interventions

Device

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 18, 2020 (Actual)
Primary completion
Jan 10, 2028 (Estimated)
Completion
Aug 10, 2029 (Estimated)
Last update posted
Sep 21, 2026

2020 – 2029

United States locations

U.S. sites
24
U.S. states
16
U.S. cities
20
Facility City State ZIP Site status
Cardiology PC Birmingham Alabama 35211 Completed
Arizona Cardiovascular Research Center Phoenix Arizona 85016 Completed
Scripps Health La Jolla California 92037 Recruiting
University of California, San Francisco San Francisco California 94143 Recruiting
Zuckerberg San Francisco General Hospital and Trauma Center San Francisco California 94143 Recruiting
Piedmont Augusta Georgia 30901 Not yet recruiting
Bluhm Cardiovascular Institute of Northwestern University Chicago Illinois 60611 Recruiting
University of Chicago Medical Center Chicago Illinois 60637 Recruiting
Prairie Education and Research Cooperative Springfield Illinois 62701 Completed
Ascension St. Vincent - Cardiovascular Research Institute Indianapolis Indiana 46260 Completed
Cardiovascular Institute of the South Houma Louisiana 70360 Recruiting
Michigan Medicine, University of Michigan Ann Arbor Michigan 48109 Recruiting
Mayo Clinic Rochester Minnesota 55905 Recruiting
St. Louis Heart and Vascular St Louis Missouri 63136 Recruiting
Weill Cornell Medicine New York New York 10021 Recruiting
Icahn School of Medicine at Mount Sinai New York New York 10029 Completed
Columbia University Medical Center New York New York 10032 Recruiting
Rochester General Hospital Rochester New York 14621 Recruiting
Duke University Medical Center Durham North Carolina 27710 Recruiting
The Christ Hospital Cincinnati Ohio 45219 Not yet recruiting
Ohio State University Wexner Medical Center Columbus Ohio 43210 Recruiting
Medical University of South Carolina Charleston South Carolina 29425 Recruiting
Baylor College of Medicine Houston Texas 77030 Recruiting
Virginia Commonwealth University Medical Center Richmond Virginia 23298 Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04592445, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 21, 2026 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04592445 live on ClinicalTrials.gov.

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