Mechanistic Evaluation of Response in TRD (MERIT)
Public ClinicalTrials.gov record NCT04608396. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
MERIT: A Randomized, Double-blind, Placebo-controlled Study of AXS-05 for Relapse Prevention in Treatment Resistant Depression
Study identification
- NCT ID
- NCT04608396
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Axsome Therapeutics, Inc.
- Industry
- Enrollment
- 44 participants
Conditions and interventions
Interventions
- AXS-05 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 12, 2020
- Primary completion
- Jul 29, 2021
- Completion
- Jul 29, 2021
- Last update posted
- Jul 11, 2022
2020 – 2021
United States locations
- U.S. sites
- 20
- U.S. states
- 12
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site | Little Rock | Arkansas | 72209 | — |
| Clinical Research Site | Redlands | California | 92374 | — |
| Clinical Research Site | Sherman Oaks | California | 91403 | — |
| Clinical Research Site | Upland | California | 91786 | — |
| Clinical Research Site | Miami | Florida | 33122 | — |
| Clinical Research Site | North Miami | Florida | 33161 | — |
| Clinical Research Site | Orlando | Florida | 32801 | — |
| Clinical Research Site | Chicago | Illinois | 606346 | — |
| Clinical Research Site | Boston | Massachusetts | 02131 | — |
| Clinical Research Site | Berlin | New Jersey | 08009 | — |
| Clinical Research Site | Rochester | New York | 14618 | — |
| Clinical Research Site | Staten Island | New York | 10312 | — |
| Clinical Research Site | Hickory | North Carolina | 28601 | — |
| Clinical Research Site | Raleigh | North Carolina | 27609 | — |
| Clinical Research Site | Cincinnati | Ohio | 45215 | — |
| Clinical Research Site | Middleburg Heights | Ohio | 44130 | — |
| Clinical Research Site | Media | Pennsylvania | 19063 | — |
| Clinical Research Site | Dallas | Texas | 75243 | — |
| Clinical Research Site | Houston | Texas | 77058 | — |
| Clinical Research Site | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04608396, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 11, 2022 · Synced May 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04608396 live on ClinicalTrials.gov.