Mechanistic Evaluation of Response in TRD (MERIT)
Public ClinicalTrials.gov record NCT04608396. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
MERIT: A Randomized, Double-blind, Placebo-controlled Study of AXS-05 for Relapse Prevention in Treatment Resistant Depression
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the relapse prevention of AXS-05 relative to placebo in subjects with treatment resistant depression (TRD). This is a randomized, double-blind, placebo-controlled study to evaluate AXS-05 compared to placebo in delaying relapse of depressive symptoms in patients with TRD who are in stable remission after treatment with AXS-05.
Study identification
- NCT ID
- NCT04608396
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 44 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 13, 2020 (Actual)
- Primary completion
- Jul 30, 2021 (Actual)
- Completion
- Jul 30, 2021 (Actual)
- Last update posted
- Jul 12, 2022
2020 – 2021
United States locations
- U.S. sites
- 20
- U.S. states
- 12
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site | Little Rock | Arkansas | 72209 | — |
| Clinical Research Site | Redlands | California | 92374 | — |
| Clinical Research Site | Sherman Oaks | California | 91403 | — |
| Clinical Research Site | Upland | California | 91786 | — |
| Clinical Research Site | Miami | Florida | 33122 | — |
| Clinical Research Site | North Miami | Florida | 33161 | — |
| Clinical Research Site | Orlando | Florida | 32801 | — |
| Clinical Research Site | Chicago | Illinois | 606346 | — |
| Clinical Research Site | Boston | Massachusetts | 02131 | — |
| Clinical Research Site | Berlin | New Jersey | 08009 | — |
| Clinical Research Site | Rochester | New York | 14618 | — |
| Clinical Research Site | Staten Island | New York | 10312 | — |
| Clinical Research Site | Hickory | North Carolina | 28601 | — |
| Clinical Research Site | Raleigh | North Carolina | 27609 | — |
| Clinical Research Site | Cincinnati | Ohio | 45215 | — |
| Clinical Research Site | Middleburg Heights | Ohio | 44130 | — |
| Clinical Research Site | Media | Pennsylvania | 19063 | — |
| Clinical Research Site | Dallas | Texas | 75243 | — |
| Clinical Research Site | Houston | Texas | 77058 | — |
| Clinical Research Site | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04608396, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 12, 2022 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04608396 live on ClinicalTrials.gov.