Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

ClinicalTrials.gov ID: NCT04614103

Public ClinicalTrials.gov record NCT04614103. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 10, 2026, 12:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (TIL or LN-145) in Patients With Metastatic Non-Small-Cell Lung Cancer

Study identification

NCT ID: NCT04614103
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Iovance Biotherapeutics, Inc.; Industry
Enrollment: 170 participants

Conditions and interventions

Conditions

Metastatic Non Small Cell Lung Cancer

Interventions

LN-145 Biological

Biological

Eligibility (public fields only)

Age range: 18 Years to 70 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 6, 2021
Primary completion: Nov 30, 2030
Completion: Nov 30, 2031
Last update posted: Apr 14, 2026

2021 – 2031

United States locations

U.S. sites: 46
U.S. states: 25
U.S. cities: 40

Facility	City	State	ZIP	Site status
Banner Health MD Anderson	Gilbert	Arizona	85234	Recruiting
City of Hope	Duarte	California	91010	Withdrawn
UC San Diego Moores Cancer Center	La Jolla	California	92037	Withdrawn
University of Southern California	Los Angeles	California	90033	Withdrawn
Christiana Care Health System	Newark	Delaware	19713	Withdrawn
University of Florida Health Cancer Center	Gainesville	Florida	32610	Withdrawn
Sylvester Comprehensive Cancer Center	Miami	Florida	33136	Recruiting
AdventHealth Cancer Institute	Orlando	Florida	32804	Withdrawn
H Lee Moffitt Cancer Center and Research Institute	Tampa	Florida	33612	Recruiting
Augusta University	Augusta	Georgia	30912	Recruiting
Rush University Medical Center	Chicago	Illinois	60612	Withdrawn
University of Illinois Hospital & Health Sciences System	Chicago	Illinois	60612	Withdrawn
Advocate Aurora Health	Park Ridge	Illinois	60068	Recruiting
University of Kentucky-Markey Cancer Center	Lexington	Kentucky	40536	Recruiting
University of Louisville	Louisville	Kentucky	40202	Recruiting
University of Maryland	Baltimore	Maryland	21201	Recruiting
Dana Farber Cancer Institute	Boston	Massachusetts	02215	Withdrawn
Karmanos Cancer Institute	Detroit	Michigan	48201	Recruiting
Henry Ford Health System	Detroit	Michigan	48202	Withdrawn
University of Minnesota	Minneapolis	Minnesota	55455	Recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
MD Anderson Cooper	Camden	New Jersey	08103	Withdrawn
Roswell Park Cancer Institute	Buffalo	New York	14263	Withdrawn
New York University Langone Medical Center	New York	New York	10016	Recruiting
Icahn School of Medicine at Mount Sinai	New York	New York	10029	Withdrawn
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
University of Rochester Medical Center	Rochester	New York	14642	Withdrawn
University of North Carolina	Chapel Hill	North Carolina	27514	Recruiting
Novant Health - Charlotte	Charlotte	North Carolina	28204	Withdrawn
Novant Health - Winston-Salem	Winston-Salem	North Carolina	27103	Recruiting
Atrium Health Wake Forest University Health Sciences	Winston-Salem	North Carolina	27157	Withdrawn
Sanford Roger Maris Cancer Center	Fargo	North Dakota	58102	Recruiting
University of Cincinnati Medical Center	Cincinnati	Ohio	45219	Recruiting
Ohio State University Comprehensive Cancer Center	Columbus	Ohio	43210	Recruiting
University of Oklahoma	Oklahoma City	Oklahoma	73104	Withdrawn
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
Allegheny General Hospital	Natrona Heights	Pennsylvania	15065	Recruiting
Fox Chase Cancer Center	Philadelphia	Pennsylvania	19111	Withdrawn
Sanford Cancer Center	Sioux Falls	South Dakota	57102	Recruiting
Avera Medical Group Cancer Institute	Sioux Falls	South Dakota	57105	Withdrawn
University of Tennessee Medical Center	Knoxville	Tennessee	37920	Recruiting
Baptist Cancer Center	Memphis	Tennessee	38120	Recruiting
Texas Oncology-Baylor Charles A. Sammons Cancer Center	Dallas	Texas	75246	Withdrawn
Houston Methodist	Houston	Texas	77030	Withdrawn
VCU Medical Center (Virginia Commonwealth University)	Richmond	Virginia	23298	Recruiting
Seattle Cancer Care Alliance	Seattle	Washington	98109	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04614103, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 14, 2026 · Synced May 10, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04614103 live on ClinicalTrials.gov.

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