Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

ClinicalTrials.gov ID: NCT04614103

Public ClinicalTrials.gov record NCT04614103. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (TIL or LN-145) in Patients With Metastatic Non-Small-Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung cancer

Study identification

NCT ID: NCT04614103
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Iovance Biotherapeutics, Inc.; Industry
Enrollment: 170 participants

Conditions and interventions

Conditions

Metastatic Non Small Cell Lung Cancer

Interventions

LN-145 Biological

Biological

Eligibility (public fields only)

Age range: 18 Years to 70 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 6, 2021
Primary completion: Nov 30, 2030
Completion: Nov 30, 2031
Last update posted: Jun 25, 2026

2021 – 2031

United States locations

U.S. sites: 27
U.S. states: 19
U.S. cities: 24

Facility	City	State	ZIP	Site status
Banner Health MD Anderson	Gilbert	Arizona	85234	Recruiting
Sylvester Comprehensive Cancer Center	Miami	Florida	33136	Active, not recruiting
H Lee Moffitt Cancer Center and Research Institute	Tampa	Florida	33612	Recruiting
Rush University Medical Center	Chicago	Illinois	60612	Active, not recruiting
University of Illinois Hospital & Health Sciences System	Chicago	Illinois	60612	Active, not recruiting
Advocate Aurora Health	Park Ridge	Illinois	60068	Recruiting
University of Louisville	Louisville	Kentucky	40202	Recruiting
University of Maryland	Baltimore	Maryland	21201	Active, not recruiting
Karmanos Cancer Institute	Detroit	Michigan	48201	Recruiting
University of Minnesota	Minneapolis	Minnesota	55455	Recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
MD Anderson Cooper	Camden	New Jersey	08103	Recruiting
New York University Langone Medical Center	New York	New York	10016	Recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
University of North Carolina	Chapel Hill	North Carolina	27514	Recruiting
Novant Health - Winston-Salem	Winston-Salem	North Carolina	27103	Active, not recruiting
Sanford Roger Maris Cancer Center	Fargo	North Dakota	58102	Recruiting
University of Cincinnati Medical Center	Cincinnati	Ohio	45219	Recruiting
Ohio State University Comprehensive Cancer Center	Columbus	Ohio	43210	Recruiting
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
Allegheny General Hospital	Natrona Heights	Pennsylvania	15065	Recruiting
Sanford Cancer Center	Sioux Falls	South Dakota	57102	Recruiting
Avera Medical Group Cancer Institute	Sioux Falls	South Dakota	57105	Active, not recruiting
University of Tennessee Medical Center	Knoxville	Tennessee	37920	Recruiting
Baptist Cancer Center	Memphis	Tennessee	38120	Recruiting
VCU Medical Center (Virginia Commonwealth University)	Richmond	Virginia	23298	Recruiting
Seattle Cancer Care Alliance	Seattle	Washington	98109	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 44 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04614103, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jun 25, 2026 · Synced Sep 2, 2026

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The complete protocol, eligibility criteria, and contact information for NCT04614103 live on ClinicalTrials.gov.

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