A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine
Public ClinicalTrials.gov record NCT04616326. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Adolescent Patients 12 to 17 Years of Age With Chronic Migraine - the REBUILD-2 Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days across the 3-month double-blind treatment period.
Study identification
- NCT ID
- NCT04616326
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 312 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 25, 2020 (Actual)
- Primary completion
- Dec 10, 2025 (Actual)
- Completion
- Mar 2027 (Estimated)
- Last update posted
- Feb 27, 2026
2020 – 2027
United States locations
- U.S. sites
- 45
- U.S. states
- 25
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rehabilitation & Neurological Services | Huntsville | Alabama | 35805 | — |
| 21st Century Neurology, a Division of Xenoscience, Inc. | Phoenix | Arizona | 85004 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Center for Neurosciences | Tucson | Arizona | 85718 | — |
| Miller Children's & Women's Hospital Long Beach | Long Beach | California | 90806 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Northwest Florida Clinical Research Group | Gulf Breeze | Florida | 32561 | — |
| Clinical Neuroscience Solutions, Inc. dba CNS Healthcare | Jacksonville | Florida | 32256 | — |
| Vitaly Clinical Research | Miami | Florida | 33125 | — |
| EMDA Clinical Research | Miami | Florida | 33126 | — |
| Bio-Medical Research LLC | Miami | Florida | 33144 | — |
| Allied Biomedical Research Institute | Miami | Florida | 33155 | — |
| Ezy Medical Research | Miami Lakes | Florida | 33015 | — |
| Wellness Clinical Research | Miami Lakes | Florida | 33016 | — |
| Avanza Medical Research Center | Pensacola | Florida | 32503 | — |
| D&H Tamarac Research Center | Tamarac | Florida | 33321 | — |
| Infinity Life Research Group | Tamarac | Florida | 33321 | — |
| USF Health | Tampa | Florida | 33612 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Medical Research Partners | Ammon | Idaho | 83406 | — |
| Northwest Clinical Trials | Boise | Idaho | 83704 | — |
| St. Alexius Medical Center | Hoffman Estates | Illinois | 60169 | — |
| Ascension Via Christi Research | Wichita | Kansas | 67214 | — |
| University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536 | — |
| Pharmasite Research, Inc. | Baltimore | Maryland | 21208 | — |
| MedVadis Research Corporation | Waltham | Massachusetts | 02451 | — |
| Minneapolis Clinic of Neurology - Burnsville Office | Burnsville | Minnesota | 55337 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| Proven Endpoints | Ridgeland | Mississippi | 39157 | — |
| Children Mercy Pediatric Clinical Research Unit | Kansas City | Missouri | 64108 | — |
| Saint Peter's University Hospital | New Brunswick | New Jersey | 08901 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Cohen Children's Northwell Health Physician Partners - Pediatric Neurology | New Hyde Park | New York | 11042 | — |
| Velocity Clinical Research at Raleigh Neurology | Raleigh | North Carolina | 27607 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Headache Center of Hope | Cincinnati | Ohio | 45236 | — |
| Providence Health & Services | Portland | Oregon | 97225 | — |
| UPMC Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Coastal Pediatric Research | Charleston | South Carolina | 29414 | — |
| Access Clinical Trials - Nashville | Nashville | Tennessee | 37203 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75235 | — |
| Prime Clinical Research - Lewisville | Lewisville | Texas | 75067 | — |
| Medical Research Partners - Logan | Logan | Utah | 84341 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Seattle Children's Hospital | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04616326, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04616326 live on ClinicalTrials.gov.