Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.
Public ClinicalTrials.gov record NCT04623242. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II/III Randomized, Double-Blind, Placebo-Controlled, Cognitive Endpoint, Multi-Center Study of Potential Disease Modifying Therapies in Individuals at Risk for and With Dominantly Inherited Alzheimer's Disease
Study identification
- NCT ID
- NCT04623242
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- Washington University School of Medicine
- Other
- Enrollment
- 194 participants
Conditions and interventions
Interventions
- Gantenerumab Drug
- Matching Placebo (Gantenerumab) Drug
- Matching Placebo (Solanezumab) Drug
- Solanezumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2012
- Primary completion
- Nov 21, 2019
- Completion
- Mar 5, 2020
- Last update posted
- Sep 21, 2022
2012 – 2020
United States locations
- U.S. sites
- 10
- U.S. states
- 10
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama in Birmingham | Birmingham | Alabama | 35294 | — |
| University of California San Diego Medical Center | La Jolla | California | 92037 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| Columbia University | New York | New York | 10032 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Butler Hospital | Providence | Rhode Island | 02096 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04623242, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2022 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04623242 live on ClinicalTrials.gov.