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Recruiting Phase 1 Interventional

A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort

ClinicalTrials.gov ID: NCT04626674

Public ClinicalTrials.gov record NCT04626674. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 9:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Systemic Gene Delivery Study Using Commercial Process Material to Evaluate the Safety of and Expression From SRP-9001 in Subjects With Duchenne Muscular Dystrophy (ENDEAVOR)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Cohort 8 (non-ambulatory participants) is currently enrolling new participants. Enrollment for Cohorts 1 through 7 has been completed. This is an open-label gene transfer therapy study evaluating the safety of and expression from delandistrogene moxeparvovec in participants with Duchenne Muscular Dystrophy (DMD). The maximum participant duration for this study is 156 weeks.

Study identification

NCT ID
NCT04626674
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Sarepta Therapeutics, Inc.
Industry
Enrollment
83 participants

Conditions and interventions

Interventions

Genetic

Eligibility (public fields only)

Age range
2 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 22, 2020
Primary completion
Dec 30, 2027
Completion
Feb 28, 2028
Last update posted
Sep 10, 2026

2020 – 2028

United States locations

U.S. sites
12
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Arkansas Children's Hospital Little Rock Arkansas 72202 Recruiting
University of California, San Diego La Jolla California 92037 Recruiting
University of California, Los Angeles Los Angeles California 90095 Recruiting
Stanford University Palo Alto California 94304 Recruiting
University of California, Davis Sacramento California 95616 Recruiting
University of Florida Gainesville Florida 32610 Recruiting
Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois 60611 Recruiting
Washington University in St. Louis St Louis Missouri 63110 Recruiting
Duke University Medical Center Durham North Carolina 27705 Recruiting
Nationwide Children's Hospital Columbus Ohio 43205 Active, not recruiting
Neurology Rare Disease Center Flower Mound Texas 75028 Recruiting
Children's Hospital of The King's Daughters Norfolk Virginia 23507 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04626674, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 10, 2026 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04626674 live on ClinicalTrials.gov.

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