ClinicalTrials.gov record
A Study of Immune System Proteins in Participants With Mild to Moderate COVID-19 Illness
ClinicalTrials.gov ID: NCT04634409
Public ClinicalTrials.gov record NCT04634409. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy and Safety of Mono and Combination Therapy With Monoclonal Antibodies in Participants With Mild to Moderate COVID-19 Illness (BLAZE-4)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to measure how well monoclonal antibodies work, either alone or in combination, against the virus that causes COVID-19. Study drug(s) will be given to participants with early symptoms of COVID-19. Samples will be taken from the back of the nose to determine how much virus is in the body at various times during the study. Participation could last about 12 or 24 weeks and includes at least 1 visit to the study site, with the remainder of assessments performed in the home, local clinic, or by phone.
Study identification
- NCT ID
- NCT04634409
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,755 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 29, 2020 (Actual)
- Primary completion
- Jul 27, 2021 (Actual)
- Completion
- Oct 18, 2021 (Actual)
- Last update posted
- Jul 1, 2022
2020 – 2021
United States locations
- U.S. sites
- 127
- U.S. states
- 31
- U.S. cities
- 106
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| The Institute for Liver Health | Mesa | Arizona | 85210 | — |
| Perseverance Research Center | Scottsdale | Arizona | 85254 | — |
| CRI of Arizona, LLC | Sun City West | Arizona | 85375 | — |
| Fiel Family and Sports Medicine PC | Tempe | Arizona | 85283 | — |
| The Institute for Liver Health | Tucson | Arizona | 85712 | — |
| KLR Business Group, Inc. dba Arkansas Clinical Research | Little Rock | Arkansas | 72205 | — |
| Applied Rsch Ctr - Arkansas Inc. | Little Rock | Arkansas | 72212 | — |
| Smart Cures Clin Research | Anaheim | California | 92806 | — |
| Hope Clinical Research | Canoga Park | California | 91303 | — |
| VCT-Covina | Covina | California | 91723 | — |
| Neighborhood Healthcare | Escondido | California | 92025 | — |
| Chemidox Clinical Trials | Lancaster | California | 93534 | — |
| Ark Clinical Research | Long Beach | California | 90806 | — |
| Long Beach Clinical Trials LLC | Long Beach | California | 90806 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048-5615 | — |
| Central Valley Research, LLC | Modesto | California | 95350 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| Sutter Institute For Medical Research | Sacramento | California | 95816 | — |
| Wolverine Clinical Trials, LLC | Santa Ana | California | 92705 | — |
| St. Joe Heritage HC-Santa Rosa | Santa Rosa | California | 95405 | — |
| Stanford University Hospital | Stanford | California | 94305 | — |
| Mazur, Statner, Dutta, Nathan | Thousand Oaks | California | 91360 | — |
| South Bay Clinical Research Institute | Torrance | California | 90503 | — |
| Infect Disease Doctors Med Grp | Walnut Creek | California | 94598 | — |
| Allianz Research Institute | Westminster | California | 92683 | — |
| Future Innovative Treatments LLC | Colorado Springs | Colorado | 80907 | — |
| Georgetown Univ Sch of Med | Washington D.C. | District of Columbia | 20007 | — |
| Synergy Healthcare LLC | Bradenton | Florida | 34208 | — |
| Holy Cross Hospital Inc. | Fort Lauderdale | Florida | 33308 | — |
| I R & Health Center, Inc. | Hialeah | Florida | 33012 | — |
| Encore Medical Research | Hollywood | Florida | 33021 | — |
| Elixia CRC | Hollywood | Florida | 33023 | — |
| Lakeland Regional Medical Center | Lakeland | Florida | 33804 | — |
| Hope Clinical Trials, Inc. | Miami | Florida | 33165 | — |
| Miami Cancer Institute at Baptist Health, Inc. | Miami | Florida | 33176 | — |
| Bio-Medical Research, LLC | Miami | Florida | 33184 | — |
| Clinical Site Partners, LLC d/b/a CSP Miami | Miami | Florida | 33186 | — |
| Panax Clinical Research | Miami Lakes | Florida | 33014 | — |
| Testing Matters Lab | Sunrise | Florida | 33325 | — |
| Advent Health Tampa | Tampa | Florida | 33613 | — |
| Triple O Research Inst | West Palm Beach | Florida | 33407 | — |
| Encore Medical Research - Weston | Weston | Florida | 33331 | — |
| Clinical Site Partners, LLC DBA CSP Orlando | Winter Park | Florida | 32789 | — |
| Gwinnett Research Inst | Buford | Georgia | 30519 | — |
| Paramount Rch Sol - College Pk | College Park | Georgia | 30349 | — |
| IACT Health - VHC | Columbus | Georgia | 31904 | — |
| Central Georgia Infectious Disease | Macon | Georgia | 31201 | — |
| Rophe Adult and Pediatric Medicine | Union City | Georgia | 30291 | — |
| Rocky Mountain Clinical Research | Idaho Falls | Idaho | 83404 | — |
| Ann & Robert H Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Franciscan Health Hammond | Dyer | Indiana | 46311 | — |
| Qualmedica Research Evansville | Evansville | Indiana | 47715 | — |
| Franciscan St. Francis Health | Indianapolis | Indiana | 46237 | — |
| St.Vincent - Indy | Indianapolis | Indiana | 46260 | — |
| Qualmedica Research, LLC | Owensboro | Kentucky | 42301 | — |
| Tandem Clinical Research,LLC | Marrero | Louisiana | 70072 | — |
| Imperial Health Urgent Care Center - Moss Bluff | Moss Bluff | Louisiana | 70611 | — |
| Nola Research Works, LLC | New Orleans | Louisiana | 70125 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| U of MA Mem Med Ctr | Worcester | Massachusetts | 01605 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Great Lakes Research Group, Inc. | Bay City | Michigan | 48706 | — |
| Revive Research Institute | Farmington Hills | Michigan | 48334 | — |
| Revival Research Institute | Sterling Heights | Michigan | 48312 | — |
| Sky Clinical Prime and Health Wellness Clinic | Fayette | Mississippi | 39069 | — |
| Olive Branch Family Medical Center | Olive Branch | Mississippi | 38654 | — |
| Sky Clin Resch - Quinn HC | Ridgeland | Mississippi | 39157 | — |
| Bio-Kinetic Clinical Applications, LLC | Springfield | Missouri | 65802 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Excel Clinical Research | Las Vegas | Nevada | 89109 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89113 | — |
| SVG Clinical | Las Vegas | Nevada | 89128 | — |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | — |
| Prime Global Research, LLC | The Bronx | New York | 10456 | — |
| Onsite Clinical Solutions, LLC | Charlotte | North Carolina | 28226 | — |
| East Carolina University | Greenville | North Carolina | 27834 | — |
| Monroe Biomed Research | Monroe | North Carolina | 28112 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| PMG Research of Wilmington | Wilmington | North Carolina | 28401 | — |
| Valley Medical Primary Care | Centerville | Ohio | 45459 | — |
| Hometown UC and Rch- Cincy | Cincinnati | Ohio | 45215 | — |
| Aventiv Research Inc | Columbus | Ohio | 43213 | — |
| Urgent Care Specialists, LLC | Columbus | Ohio | 43214 | — |
| Remington-Davis, Inc | Columbus | Ohio | 43215 | — |
| Urgent Care Specialists, LLC | Dayton | Ohio | 45424 | — |
| META Medical Research Institute | Dayton | Ohio | 45432 | — |
| Ascension St. John Tulsa OK | Tulsa | Oklahoma | 74104 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 18901 | — |
| Jefferson Hosp for Neurosci | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| VITALINK - Anderson | Anderson | South Carolina | 29621 | — |
| Carolina Medical Research - Clinton | Clinton | South Carolina | 29325 | — |
| VITALINK - Gaffney | Gaffney | South Carolina | 29340 | — |
| Carolina Medical Research - Greenville | Greenville | South Carolina | 29607 | — |
| VITALINK - Greenville | Greenville | South Carolina | 29615 | — |
| VITALINK - Spartanburg | Spartanburg | South Carolina | 29303 | — |
| VITALINK - Union | Union | South Carolina | 29379 | — |
| Univ Diab & Endo Consult | Chattanooga | Tennessee | 37411 | — |
| New Phase Research and Development | Knoxville | Tennessee | 37909 | — |
| Gadolin Research, LLC | Beaumont | Texas | 77702 | — |
| Conroe Willis Medical Research | Conroe | Texas | 77304 | — |
| Crossroads Clinical Research | Corpus Christi | Texas | 78413 | — |
| B S & W Med Center | Dallas | Texas | 75246 | — |
| Baylor - Fort Worth | Fort Worth | Texas | 76104 | — |
| North Texas Clinical Trials, LLC | Fort Worth | Texas | 76104 | — |
| Houston Methodist Research Ins | Houston | Texas | 77030 | — |
| Next Level Urgent Care | Houston | Texas | 77057 | — |
| Accurate Clinical Management, LLC. | Houston | Texas | 77065 | — |
| 1960 Family Practice, PA | Houston | Texas | 77090 | — |
| B S & W Med Center | Irving | Texas | 75061 | — |
| Zion Urgent Care Clinic | Katy | Texas | 77494 | — |
| BioPharma Family Practice Center McAllen | McAllen | Texas | 78501 | — |
| BRCR Medical Center, Inc | McAllen | Texas | 78501 | — |
| North Hills Medical Research | North Richland Hills | Texas | 76180 | — |
| Bay Area Infectious Diseases Associates | Pasadena | Texas | 77505 | — |
| Epic Medical Research | Red Oak | Texas | 75154 | — |
| Baylor - Round Rock | Round Rock | Texas | 78665 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| APD Clinical Research | Splendora | Texas | 77372 | — |
| Crossroads Clin Rch-Victoria | Victoria | Texas | 77901 | — |
| CLS Research Ctr, PLLC | Webster | Texas | 77598 | — |
| CARE ID | Annandale | Virginia | 22003 | — |
| Evergreen Health Research | Kirkland | Washington | 98034 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04634409, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2022 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04634409 live on ClinicalTrials.gov.