CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT04637763. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
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Official title
A Phase 1, Multicenter, Open-Label Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy in Patients With Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
CB010A is a study evaluating safety, emerging efficacy, pharmacokinetics and immunogenicity of CB-010 in adults with relapsed/refractory B cell non-Hodgkin lymphoma after lymphodepletion consisting of cyclophosphamide and fludarabine.
Study identification
- NCT ID
- NCT04637763
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 72 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 26, 2021 (Actual)
- Primary completion
- Sep 11, 2025 (Actual)
- Completion
- Dec 31, 2026 (Estimated)
- Last update posted
- Oct 19, 2026
2021 – 2026
United States locations
- U.S. sites
- 31
- U.S. states
- 20
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | — |
| HonorHealth | Scottsdale | Arizona | 85258 | — |
| University of Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas | Little Rock | Arkansas | 72205 | — |
| University of California San Diego Moores Cancer Center | La Jolla | California | 92073 | — |
| University of Southern California, Norris Comprehensive Cancer Center | Los Angeles | California | 90089 | — |
| Chao Family Comprehensive Cancer Center/University of California Irvine | Orange | California | 92868 | — |
| Advent Health | Orlando | Florida | 32803 | — |
| Bone and Marrow Transplant Group of Georgia | Atlanta | Georgia | 30342 | — |
| Augusta University/Georgia Cancer Center | Augusta | Georgia | 30912 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40207 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Regional Cancer Care Associates LLC - Hackensack | Hackensack | New Jersey | 07601 | — |
| Atlantic Health System | Morristown | New Jersey | 07960 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Montefiore Medical Center | New York | New York | 10461 | — |
| Oncology Hematology Care | Cincinnati | Ohio | 45242 | — |
| Ohio State University Medical Group | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University (OHSU) | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37323 | — |
| Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Huntsman Cancer Institute at the University of Utah | Salt Lake City | Utah | 84112 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Virginia Commonwealth University (VCU) | Richmond | Virginia | 23219 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04637763, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 19, 2026 · Synced Nov 12, 2026
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