Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease
Public ClinicalTrials.gov record NCT04639050. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase Ib/IIa, Randomized, Double Blind, Placebo-Controlled, Multiple Ascending Dose, Parallel-Group Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Patients With Prodromal or Mild to Moderate Alzheimer's Disease
Study identification
- NCT ID
- NCT04639050
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 241 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- RO7126209 Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 14, 2021
- Primary completion
- Jun 29, 2030
- Completion
- Jun 29, 2030
- Last update posted
- Mar 17, 2026
2021 – 2030
United States locations
- U.S. sites
- 17
- U.S. states
- 6
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| JEM Research LLC | Atlantis | Florida | 33462 | — |
| K2 Medical Research-Winter Garden | Clermont | Florida | 34711 | — |
| K2 Medical Research - The Villages | Lady Lake | Florida | 32159 | — |
| K2 Medical Research, LLC | Maitland | Florida | 32751 | — |
| Optimus U Corp | Miami | Florida | 33135 | — |
| Charter Research - Winter Park/Orlando | Orlando | Florida | 32803 | — |
| Advent Health Orlando | Orlando | Florida | 32804 | — |
| Alzheimer's Research and Treatment Center | Stuart | Florida | 34997 | — |
| Charter Research - Lady Lake/The Villages | The Villages | Florida | 32162 | — |
| Alzheimer?s Research and Treatment Center | Wellington | Florida | 33414 | — |
| Conquest Research, LLC | Winter Park | Florida | 32789 | — |
| Alzheimer's Research and Treatment Center - Columbus | Columbus | Georgia | 31904 | — |
| Center for Advanced Research & Education | Gainesville | Georgia | 30501 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Summit Research Network Inc. | Portland | Oregon | 97210 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Kerwin Research Center, LLC | Dallas | Texas | 75231 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04639050, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 17, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04639050 live on ClinicalTrials.gov.