A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder
Public ClinicalTrials.gov record NCT04658862. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-center, Randomized Study Evaluating Efficacy of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-Invasive Urothelial Carcinoma (MIBC) of the Bladder Who Are Not Receiving Radical Cystectomy
Study identification
- NCT ID
- NCT04658862
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Enrollment
- 518 participants
Conditions and interventions
Conditions
Interventions
- Cetrelimab Biological
- Cisplatin Drug
- Conventional radiation therapy Radiation
- Gemcitabine Drug
- Hypo-fractioned radiation therapy Radiation
- TAR-200 Drug
Biological · Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 6, 2020
- Primary completion
- Dec 29, 2026
- Completion
- Dec 30, 2028
- Last update posted
- May 7, 2026
2020 – 2028
United States locations
- U.S. sites
- 28
- U.S. states
- 17
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Loma Linda Univ Faculty Medic | Loma Linda | California | 92354 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Providence Saint John s Health Center | Santa Monica | California | 90404 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| The Urology Center of Colorado | Denver | Colorado | 80211 | — |
| Foothills Urology - Golden Off | Golden | Colorado | 80401 | — |
| Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | — |
| Urological Research Network | Hialeah | Florida | 33016 | — |
| Memorial Healthcare System | Pembroke Pines | Florida | 33028 | — |
| Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322 | — |
| DuPage Medical Group | Lisle | Illinois | 60532 | — |
| University Hospitals Seidman Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Michigan Institute of Urology | Troy | Michigan | 48084 | — |
| Adult Pediatric Urology & Urogynecology, P.C | Omaha | Nebraska | 68114 | — |
| Garden State Urology | Morristown | New Jersey | 07960 | — |
| New Jersey Urology LLC | Voorhees Township | New Jersey | 08043 | — |
| Cardiology Clinic at Montefiore Hutchinson Complex | The Bronx | New York | 10461 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Vidant Urology - Greenville | Greenville | North Carolina | 27834 | — |
| Wake Forest University Baptist Medical Center (WFUBMC) - Comprehensive Cancer Center | Winston-Salem | North Carolina | 27103 | — |
| Wexner Medical Center at the Ohio State University | Columbus | Ohio | 43210 | — |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | — |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| Houston Metro Urology | Houston | Texas | 77027 | — |
| University of Texas Medical Branch | League City | Texas | 77573 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 262 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04658862, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04658862 live on ClinicalTrials.gov.