SPI-1005 for the Treatment of Meniere's Disease
Public ClinicalTrials.gov record NCT04677972. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of SPI-1005 in Meniere's Disease and Open Label Extension Study to Evaluate the Chronic Safety of SPI-1005
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial (RCT) with open-label extension study (OLE), of SPI-1005 in adult subjects with definite Meniere's disease with active symptoms within three months preceding study enrollment.
Study identification
- NCT ID
- NCT04677972
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 220 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 1, 2022
- Primary completion
- Sep 18, 2023
- Completion
- Jul 24, 2024
- Last update posted
- Jul 22, 2026
2022 – 2024
United States locations
- U.S. sites
- 12
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| House Clinic | Los Angeles | California | 90057 | — |
| Sacramento Ear, Nose, & Throat | Roseville | California | 95661 | — |
| George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| ENT and Allergy Associates of Florida | Boca Raton | Florida | 33487 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66160 | — |
| Advanced ENT & Allergy | Louisville | Kentucky | 40207 | — |
| Piedmont Ear, Nose & Throat Associates | Winston-Salem | North Carolina | 27103 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19144 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04677972, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 22, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04677972 live on ClinicalTrials.gov.