Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT
Public ClinicalTrials.gov record NCT04678154. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT - A Multicenter Randomized Control Trial
Study identification
- NCT ID
- NCT04678154
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Enrollment
- 1,200 participants
Conditions and interventions
Conditions
Interventions
- Standard of care Drug
- Vancomycin and Tobramycin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 6, 2021
- Primary completion
- Sep 29, 2026
- Completion
- Mar 30, 2027
- Last update posted
- May 12, 2025
2021 – 2027
United States locations
- U.S. sites
- 31
- U.S. states
- 21
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford University | Redwood City | California | 94063 | Recruiting |
| _University of California, San Francisco | San Francisco | California | 94110 | Recruiting |
| University of California at San Francisco | San Francisco | California | 94110 | Recruiting |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | Recruiting |
| St Mary's University/Tenent Health | West Palm Beach | Florida | 33407 | Recruiting |
| Emory University School of Medicine | Atlanta | Georgia | 30303 | Recruiting |
| Indiana University School of Medicine - Methodist Hospital | Indianapolis | Indiana | 46202 | Recruiting |
| Indiana University/Eskenazi Health | Indianapolis | Indiana | 46202 | Recruiting |
| University of Kentucky | Lexington | Kentucky | 40506 | Recruiting |
| LSU Health Sciences | New Orleans | Louisiana | 70112 | Recruiting |
| University of Maryland , MD Department of Orthopaedics | Baltimore | Maryland | 21201 | Recruiting |
| Walter Reed Military Medical Center | Bethesda | Maryland | 20889 | Recruiting |
| Harvard/Mass General/Brigham Hospitals | Boston | Massachusetts | 02115 | Recruiting |
| Hennepin County Medical Center / Minneapolis | Minneapolis | Minnesota | 55415 | Recruiting |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | Recruiting |
| Dartmouth Hitchcock | Lebanon | New Hampshire | 03766 | Recruiting |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | Recruiting |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27514 | Recruiting |
| Atrium Health Carolinas Medical Center | Charlotte | North Carolina | 28203 | Recruiting |
| Atrium Health Wake Forest Baptist | Winston-Salem | North Carolina | 27157 | Recruiting |
| METROHealth | Cleveland | Ohio | 44109 | Recruiting |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43201 | Recruiting |
| University of Oklahoma College of Medicine | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Temple University | Philadelphia | Pennsylvania | 19140 | Recruiting |
| Brown University/Rhode Island Hospital | Providence | Rhode Island | 02905 | Recruiting |
| Rhode Island Hospital/Brown University | Providence | Rhode Island | 02905 | Recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | Recruiting |
| University of Texas Health Science Center - Houston | Houston | Texas | 77030 | Recruiting |
| University of Virginia | Charlottesville | Virginia | 22903 | Recruiting |
| Inova Fairfax MEdical Campus | Falls Church | Virginia | 22042 | Recruiting |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04678154, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 12, 2025 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04678154 live on ClinicalTrials.gov.