ClinicalTrials.gov record
Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus
ClinicalTrials.gov ID: NCT04680637
Public ClinicalTrials.gov record NCT04680637. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 14, 2026, 2:21 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Dose Ranging Study to Evaluate the Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus With Inadequate Response to Standard of Care Therapy
Study identification
- NCT ID
- NCT04680637
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 168 participants
Conditions and interventions
Conditions
Interventions
- Efavaleukin Alfa Drug
- Placebo Drug
- Standard of Care Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 5, 2021
- Primary completion
- May 21, 2023
- Completion
- May 21, 2023
- Last update posted
- Jun 27, 2024
2021 – 2023
United States locations
- U.S. sites
- 51
- U.S. states
- 15
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham,Arthritis Clinical Intervention Program | Birmingham | Alabama | 35294 | — |
| Arizona Arthritis and Rheumatology Associates PC | Gilbert | Arizona | 85297 | — |
| Arizona Arthritis And Rheumatology Associates PC | Glendale | Arizona | 85306 | — |
| Arizona Arthritis and Rheumatology Associates PC | Tucson | Arizona | 85704 | — |
| Loma Linda University Health Care | Loma Linda | California | 92354 | — |
| University of California Los Angeles | Los Angeles | California | 90024 | — |
| University of California Irvine | Orange | California | 92868 | — |
| Robin K Dore MD Inc | Tustin | California | 92780 | — |
| Arthritis and Rheumatic Disease Specialties | Aventura | Florida | 33180 | — |
| Life Clinical Trials | Aventura | Florida | 33180 | — |
| Centre for Rheumatology Immunology and Arthritis | Fort Lauderdale | Florida | 33309 | — |
| GNP Research | Hollywood | Florida | 33024 | — |
| Millennium Research | Ormond Beach | Florida | 32174 | — |
| Integral Rheumatology and Immunology Specialists | Plantation | Florida | 33324 | — |
| Suncoast Medical Clinic | St. Petersburg | Florida | 33710 | — |
| Baycare Medical Group Inc | Tampa | Florida | 33614 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Greater Chicago Specialty Physicians | Schaumburg | Illinois | 60195 | — |
| Clinic of Robert Hozman, MD - Clinical Investigational Specialists, Inc | Skokie | Illinois | 60076 | — |
| Western Kentucky Rheumatology PLLC | Hopkinsville | Kentucky | 42240 | — |
| Accurate Clinical Research | Lake Charles | Louisiana | 70605 | — |
| Michigan Rheumatology Group, PC - Grand Blanc Office | Grand Blanc | Michigan | 48439 | — |
| Arthritis and Rheumatology of Michigan | Lansing | Michigan | 48910 | — |
| New York University Langone Ambulatory Care Brooklyn Heights | Brooklyn | New York | 11201 | — |
| Feinstein Institute for Medical Research | Manhasset | New York | 11030 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Institute for Clinical and Translation Research at Einstein and Montefiore Clinical Research Center | The Bronx | New York | 10461 | — |
| University of North Carolina at Chapel Hill Thurston Arthritis Research Center | Chapel Hill | North Carolina | 27599 | — |
| Joint and Muscle Research Institute | Charlotte | North Carolina | 28204 | — |
| DJL Clinical Research PLLC | Charlotte | North Carolina | 28210 | — |
| Javara | Charlotte | North Carolina | 28210 | — |
| Atrium Health Rheumatology | Charlotte | North Carolina | 28211 | — |
| Arthritis and Rheumatology Center of Oklahoma PLLC | Oklahoma City | Oklahoma | 73102 | — |
| Oklahoma Medical Research Foundation | Oklahoma City | Oklahoma | 73104 | — |
| University of Pittsburgh Medical Center Lupus Center of Excellence | Pittsburgh | Pennsylvania | 15213 | — |
| Columbia Arthritis Center, PA | Columbia | South Carolina | 29204 | — |
| Piedmont Arthritis Clinic | Greenville | South Carolina | 29601 | — |
| West Tennessee Research Institute, LLC | Jackson | Tennessee | 38305 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| Ramesh C Gupta MD | Memphis | Tennessee | 38119 | — |
| Arthritis and Rheumatology Institute | Allen | Texas | 75013 | — |
| Precision Comprehensive Clinical Research Solutions | Colleyville | Texas | 76034 | — |
| Texas Arthritis Center PA | El Paso | Texas | 79902 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Accurate Clinical Management | Houston | Texas | 77084 | — |
| Laila A Hassan, MD, PA | Houston | Texas | 77089 | — |
| Trinity Universal Research Associates, LLC | Plano | Texas | 75024 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| University of Texas Health Science Center at San Antonio Medical Arts Research Clinic Marc | San Antonio | Texas | 78229 | — |
| Arthritis and Osteoporosis Clinic | Waco | Texas | 76710 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 99 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04680637, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 27, 2024 · Synced May 14, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04680637 live on ClinicalTrials.gov.