A Study of Auxora in Patients With Acute Pancreatitis and Accompanying SIRS
Public ClinicalTrials.gov record NCT04681066. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo Controlled Dose-Ranging Study of Auxora in Patients With Acute Pancreatitis and Accompanying Systemic Inflammatory Response Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Approximately 216 patients with acute pancreatitis and accompanying SIRS will be randomized at approximately 30 sites. Patients will be randomly assigned to either Auxora at one of three dose levels or one of three placebo volumes to maintain the double-blind. Study drug infusions will occur every 24 hours for three consecutive days for a total of three infusions. Patients will remain hospitalized as per standard of care and once discharged will be asked to complete a daily meal diary and return for a Day 30 safety assessment. It is recommended that patients randomized in the study should not be discharged from the hospital until solid food is tolerated, abdominal pain has resolved or been adequately controlled, and there is no clinical evidence of infection necessitating continued hospitalization.
Study identification
- NCT ID
- NCT04681066
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 216 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 24, 2021 (Actual)
- Primary completion
- May 15, 2024 (Actual)
- Completion
- May 15, 2024 (Actual)
- Last update posted
- Aug 24, 2026
2021 – 2024
United States locations
- U.S. sites
- 27
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Long Beach Medical Center | Long Beach | California | 90806 | — |
| LA County Hospital - USC | Los Angeles | California | 90033 | — |
| Cedars Sinai | Los Angeles | California | 90048 | — |
| University of California at Irvine Medical Center | Orange | California | 92868 | — |
| Harbor UCLA Medical Center | Torrance | California | 90502 | — |
| Torrance Memorial Medical Center | Torrance | California | 90505 | — |
| The Stamford Hospital | Stamford | Connecticut | 06902 | — |
| Sarasota Memorial Health Care System | Sarasota | Florida | 34239 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| St. Luke's Regional Medical Center | Boise | Idaho | 83712 | — |
| Northwestern University Hospital | Chicago | Illinois | 60611 | — |
| Robley Rex VA Medical Center | Louisville | Kentucky | 40206 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Methodist Hospital | Saint Louis Park | Minnesota | 55426 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| University of Missouri School of Medicine | Columbia | Missouri | 65212 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Northshore University Hospital | Manhasset | New York | 11030 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Ohio State University | Columbus | Ohio | 43201 | — |
| Regional One Health | Memphis | Tennessee | 38106 | — |
| John Peter Smith Hospital | Fort Worth | Texas | 76104 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| UT Health Houston | Houston | Texas | 77030 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| CAMC Institute for Academic Medicine | Charleston | West Virginia | 25304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04681066, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2026 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04681066 live on ClinicalTrials.gov.