A Study of PY314 in Subjects With Advanced Solid Tumors
Public ClinicalTrials.gov record NCT04691375. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1a/1b Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PY314 as a Single Agent and In Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Study identification
- NCT ID
- NCT04691375
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Ikena Oncology
- Industry
- Enrollment
- 86 participants
Conditions and interventions
Conditions
Interventions
- Combination Therapy: PY314 + Pembrolizumab Drug
- PY314 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 28, 2020
- Primary completion
- Aug 30, 2023
- Completion
- Sep 21, 2023
- Last update posted
- Mar 21, 2024
2020 – 2023
United States locations
- U.S. sites
- 23
- U.S. states
- 17
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Scottsdale - PPDS | Phoenix | Arizona | 85054 | — |
| Honor Health Research Institute | Scottsdale | Arizona | 85258-4566 | — |
| City of Hope - Comprehensive Cancer Center | Duarte | California | 91010 | — |
| Stanford Hospital and Clinics | Palo Alto | California | 94304 | — |
| UC San Diego Moores Cancer Center | San Diego | California | 92093 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Mayo Clinic Jacksonville - PPDS | Jacksonville | Florida | 32224 | — |
| H Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02214 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Mayo Clinic - PPDS | Rochester | Minnesota | 55905 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| University of Oklahoma Peggy and Charles Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| OHSU Knight Cancer Institute Beaverton Clinic | Portland | Oregon | 97239 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Vanderbilt Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Start South Texas Accelerated Research Therapeutics | San Antonio | Texas | 78229 | — |
| NEXT Virginia | Fairfax | Virginia | 22031 | — |
| Wisconsin Institutes for Medical Research | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04691375, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 21, 2024 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04691375 live on ClinicalTrials.gov.