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Recruiting Phase 2 Interventional

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

ClinicalTrials.gov ID: NCT04696029

Public ClinicalTrials.gov record NCT04696029. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 10:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Trial of Eflornithine/DFMO as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma

Study identification

NCT ID
NCT04696029
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Giselle Sholler
Other
Enrollment
118 participants

Conditions and interventions

Interventions

  • Difluoromethylornithine Drug

Drug

Eligibility (public fields only)

Age range
Up to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 28, 2021
Primary completion
Feb 29, 2028
Completion
Feb 28, 2029
Last update posted
Apr 27, 2026

2021 – 2029

United States locations

U.S. sites
23
U.S. states
16
U.S. cities
23
Facility City State ZIP Site status
Arkansas Children's Hospital Little Rock Arkansas 72202 Recruiting
UCSF Benioff Children's Hospital Oakland Oakland California 94609 Recruiting
Rady Children's Hospital San Diego California 92123 Recruiting
Stanford University Stanford California 94305 Recruiting
Connecticut Children's Hospital Hartford Connecticut 06106 Recruiting
Nicklaus Children's Hospital Miami Florida 33155 Recruiting
Arnold Palmer Hospital for Children Orlando Florida 32806 Recruiting
All Children's Hospital Johns Hopkins Medicine St. Petersburg Florida 33701 Recruiting
St. Joseph's Children's Hospital Tampa Florida 33607 Recruiting
Kapiolani Medical Center for Women and Children Honolulu Hawaii 96813 Recruiting
Advocate Aurora Research Institute Chicago Illinois 60453 Recruiting
Kentucky Children's Hospital Lexington Kentucky 40502 Recruiting
Norton Children's Research Institute/Affiliated with University of Louisville School of Medicine Louisville Kentucky 40202 Recruiting
Children's Mercy Hospitals and Clinics Kansas City Missouri 64108 Recruiting
Cardinal Glennon Children's Medical Center St Louis Missouri 63104 Recruiting
Hackensack University Medical Center Hackensack New Jersey 07601 Recruiting
Levine Children's Hospital Charlotte North Carolina 28204 Recruiting
University of Oklahoma Oklahoma City Oklahoma 73104 Recruiting
Randall Children's Hospital Portland Oregon 97227 Recruiting
Penn State Milton S. Hershey Medical Center and Children's Hospital Hershey Pennsylvania 17033 Recruiting
Hasbro Children's Hospital Providence Rhode Island 02903 Recruiting
Medical University of South Carolina Charleston South Carolina 29425 Recruiting
Dell Children's Blood and Cancer Center Austin Texas 78723 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04696029, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 27, 2026 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04696029 live on ClinicalTrials.gov.

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