ClinicalTrials.gov record
Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov ID: NCT04708782
Public ClinicalTrials.gov record NCT04708782. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis (TETON-1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study RIN-PF-301 is designed to evaluate the superiority of inhaled treprostinil against placebo for the change in absolute forced vital capacity (FVC) from baseline to Week 52.
Study identification
- NCT ID
- NCT04708782
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 598 participants
Conditions and interventions
Interventions
- Placebo Drug
- Inhaled Treprostinil Drug
- Treprostinil Ultrasonic Nebulizer Device
Drug · Device
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 1, 2021 (Actual)
- Primary completion
- Feb 2, 2026 (Actual)
- Completion
- Feb 2, 2026 (Actual)
- Last update posted
- May 5, 2026
2021 – 2026
United States locations
- U.S. sites
- 90
- U.S. states
- 32
- U.S. cities
- 76
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Banner University Medical Center-Phoenix | Phoenix | Arizona | 85006 | — |
| Arizona Pulmonary Specialists, Ltd. | Phoenix | Arizona | 85012 | — |
| St. Joseph's Hospital and Medical Center - Norton Thoracic Institute | Phoenix | Arizona | 85013 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| UC San Diego Health | La Jolla | California | 92037 | — |
| David Geffen School of Medicine at UCLA | Los Angeles | California | 90095 | — |
| NewportNativeMD, Inc | Newport Beach | California | 92663 | — |
| University of California, Irvine | Orange | California | 92868 | — |
| Palmtree Clinical Research, Inc. | Palm Springs | California | 92262 | — |
| UC Davis Health Medical Center | Sacramento | California | 95817 | — |
| University of California - San Francisco | San Francisco | California | 94143 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| St. Francis Sleep Allergy & Lung Institute | Clearwater | Florida | 33765 | — |
| University of Florida Health at Shands | Gainesville | Florida | 32610 | — |
| Ascension St. Vincent's | Jacksonville | Florida | 32204 | — |
| University of Florida | Jacksonville | Florida | 32209 | — |
| Mayo Clinic Florida | Jacksonville | Florida | 32224 | — |
| Pulmonary Disease Specialists, PA d/b/a PDS Research | Kissimmee | Florida | 34741 | — |
| Central Florida Pulmonary Group, PA | Orlando | Florida | 32803 | — |
| Coastal Pulmonary & Critical Care PLC | St. Petersburg | Florida | 33704 | — |
| University of South Florida Health | Tampa | Florida | 33606 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Piedmont Healthcare Atlanta | Atlanta | Georgia | 30309 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| The Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Rush University Medical Center Outpatient Pulmonary Clinic | Chicago | Illinois | 60612 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Community Health Network | Indianapolis | Indiana | 46250 | — |
| The University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Norton Pulmonary Specialists | Louisville | Kentucky | 40202 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| LSU Health Sciences Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Tulane University Medical Center | New Orleans | Louisiana | 70112 | — |
| LSU Health Science Center Shreveport | Shreveport | Louisiana | 71103 | — |
| Johns Hopkins Asthma & Allergy Center | Baltimore | Maryland | 21224 | — |
| Adventist Healthcare White Oak Medical CEnter | Silver Spring | Maryland | 20904 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan Int Med Pulmonary and critical care | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Corewell Health William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55902 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| The Lung Research Center | Chesterfield | Missouri | 63017 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Creighton University Clinical Research Office | Omaha | Nebraska | 68124 | — |
| University of New Mexico Health Sciences Center | Albuquerque | New Mexico | 87106 | — |
| St Joseph's Physician's Pulmonary Health | Liverpool | New York | 13088 | — |
| Northwell Health | New Hyde Park | New York | 11040 | — |
| University of Rochester Medical center | Rochester | New York | 14642 | — |
| Stony Brook Advanced Specialty Care | Stony Brook | New York | 11725 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| PulmonIx, LLC | Greensboro | North Carolina | 27403 | — |
| East Carolina University and Leo Jenkins Cancer Center | Greenville | North Carolina | 27834 | — |
| Southeastern Research Center | Winston-Salem | North Carolina | 27103 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center - Martha Morehouse Medical Pavilion | Columbus | Ohio | 43221 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| The Oregon Clinic, PC | Portland | Oregon | 97220 | — |
| Penn State Milton S. Hershey Medical Center/Penn State College of Medicine | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thoams Jefferson,Hospital University | Philadelphia | Pennsylvania | 19107 | — |
| Temple Lung Center | Philadelphia | Pennsylvania | 19140 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Prisma Health Midlands | Columbia | South Carolina | 29203 | — |
| Clinical Research of Rock Hill | Rock Hill | South Carolina | 29732 | — |
| Statecare Pulmonary Consultants | Knoxville | Tennessee | 37919 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37204 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| Univrsity of Texas Southwestern Medical Center | Dallas | Texas | 75390-8550 | — |
| Premier Pulmonary Critical Care and Sleep Medicine | Denison | Texas | 75020 | — |
| Baylor Clinic-Baylor College of Medicine | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| A & A Research Consultants, LLC | McAllen | Texas | 78503 | — |
| Metroplex Pulmonary and Sleep Center PA | McKinney | Texas | 75069 | — |
| Renovatio Clinical Consultants, LLC | The Woodlands | Texas | 77380 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Utah Health | Salt Lake City | Utah | 84108 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22903 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Pulmonary Associates of Richmond, Inc. | Richmond | Virginia | 23230 | — |
| University of Wisconsin School of Medicine and Public health | Madison | Wisconsin | 53792 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04708782, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced Nov 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04708782 live on ClinicalTrials.gov.