ClinicalTrials.gov record
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Study of SAR444881 Administered Alone and in Combination With Other Therapeutics in Participants With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT04717375

Public ClinicalTrials.gov record NCT04717375. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:32 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2, Dose Escalation, Dose Expansion, and Dose Optimization Study of the Safety, Tolerability, and Anti-tumor Activity of SAR444881 Administered Alone and in Combination With Pembrolizumab, Cetuximab and/or Chemotherapy in Participants With Advanced Solid Tumors

Study identification

NCT ID
NCT04717375
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Sanofi
Industry
Enrollment
125 participants

Conditions and interventions

Interventions

  • Carboplatin Drug
  • Cetuximab Drug
  • Pembrolizumab Drug
  • Pemetrexed Drug
  • SAR444881 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 10, 2021
Primary completion
Jul 1, 2025
Completion
Jul 1, 2025
Last update posted
Aug 6, 2025

2021 – 2025

United States locations

U.S. sites
9
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
Mayo Clinic Hospital- Site Number : 8400003 Phoenix Arizona 85054-4504
City of Hope Comprehensive Cancer Center- Site Number : 8400002 Duarte California 91030
University of Colorado- Site Number : 8400012 Aurora Colorado 80045
Smilow Cancer Center at Yale-New Haven- Site Number : 8400001 New Haven Connecticut 06511
Clermont Oncology Center- Site Number : 8400005 Clermont Florida 34711
Mid Florida Hematology and Oncology Center- Site Number : 8400006 Orange City Florida 32763
Mercy Cancer Center - MercyOne Richard Deming Cancer Center- Site Number : 8400011 Des Moines Iowa 50314
Norton Cancer Institute - Downtown Women's Cancer Center- Site Number : 8400004 Louisville Kentucky 40202
Mayo Clinic Hospital Rochester- Site Number : 8400007 Rochester Minnesota 55905

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04717375, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 6, 2025 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04717375 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →