A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)
Public ClinicalTrials.gov record NCT04718675. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 1, First-in-human, Open-label Dose Escalation and Cohort Expansion Study of KB-0742 in Patients With Relapsed or Refractory Solid Tumors or Non-Hodgkin Lymphoma
Study identification
- NCT ID
- NCT04718675
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Kronos Bio
- Industry
- Enrollment
- 135 participants
Conditions and interventions
Conditions
Interventions
- KB-0742 Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 7, 2021
- Primary completion
- Jan 6, 2025
- Completion
- Feb 6, 2025
- Last update posted
- Feb 16, 2025
2021 – 2025
United States locations
- U.S. sites
- 20
- U.S. states
- 11
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| O'Neal Comprehensive Cancer Center at the University of Alabama | Birmingham | Alabama | 35233 | — |
| City of Hope | Duarte | California | 91010 | — |
| MemorialCare - Orange Coast Medical Center | Fountain Valley | California | 92708 | — |
| City of Hope - Orange County Lennar Foundation Cancer Center | Irvine | California | 92618 | — |
| Precision NextGen Oncology | Los Angeles | California | 90025 | — |
| Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| University of California, Los Angeles (UCLA) | Los Angeles | California | 90095 | — |
| Community Health Network Community Cancer Center South | Indianapolis | Indiana | 46227 | — |
| Community Health Network Community Cancer Center North | Indianapolis | Indiana | 46250 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Michigan Rogel Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Cleveland Clinic - Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Pennsylvania Cancer Specialists Research Institute - Gettysburg Cancer Center | Gettysburg | Pennsylvania | 17325 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| SCRI Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04718675, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 16, 2025 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04718675 live on ClinicalTrials.gov.