Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia
Public ClinicalTrials.gov record NCT04720534. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Placebo-Controlled Phase 2b Study to Evaluate the Efficacy and Safety of ARO-APOC3 in Adults With Severe Hypertriglyceridemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of AROAPOC3-2001 is to evaluate the efficacy and safety of ARO-APOC3 in participants with severe hypertriglyceridemia. Participants will receive 2 subcutaneous injections of ARO-APOC3.
Study identification
- NCT ID
- NCT04720534
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 229 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2021 (Actual)
- Primary completion
- Mar 9, 2023 (Actual)
- Completion
- Aug 31, 2023 (Actual)
- Last update posted
- Mar 24, 2026
2021 – 2023
United States locations
- U.S. sites
- 33
- U.S. states
- 19
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site 2 | Beverly Hills | California | 90211 | — |
| Research Site 4 | Palm Springs | California | 92292 | — |
| Research Site 5 | Boca Raton | Florida | 33434 | — |
| Research Site 6 | Fort Lauderdale | Florida | 33308 | — |
| Research Site 10 | Miami | Florida | 33144 | — |
| Research Site 9 | Miami | Florida | 33144 | — |
| Research Site 11 | Miami | Florida | 33155 | — |
| Research Site 8 | Miami | Florida | 33173 | — |
| Research Site 12 | Miami Springs | Florida | 33166 | — |
| Research Site 14 | Port Orange | Florida | 32127 | — |
| Research Site 16 | Dunwoody | Georgia | 30338 | — |
| Research Site 17 | Arlington Heights | Illinois | 60005 | — |
| Research Site 18 | Lexington | Kentucky | 40503 | — |
| Research Site 20 | Minneapolis | Minnesota | 55455 | — |
| Research Site 21 | Tupelo | Mississippi | 38801 | — |
| Research Site 22 | Kalispell | Montana | 59901 | — |
| Research Site 23 | Omaha | Nebraska | 68114 | — |
| Research Site 24 | Las Vegas | Nevada | 89121 | — |
| Research Site 25 | Long Island City | New York | 11106 | — |
| Research Site 26 | New Windsor | New York | 12553 | — |
| Research Site 27 | New York | New York | 10029 | — |
| Research Site 29 | Morehead City | North Carolina | 28557 | — |
| Research Site 30 | Fargo | North Dakota | 58104 | — |
| Research Site 31 | Dayton | Ohio | 45419 | — |
| Research Site 32 | Franklin | Ohio | 45005 | — |
| Research Site 33 | Maumee | Ohio | 43537 | — |
| Research Site 34 | Oklahoma City | Oklahoma | 73135 | — |
| Research Site 35 | Greenville | South Carolina | 29607 | — |
| Research Site 36 | Chattanooga | Tennessee | 37421 | — |
| Research Site 38 | Houston | Texas | 77030 | — |
| Research Site 39 | Houston | Texas | 77099 | — |
| Research Site 40 | San Antonio | Texas | 78249 | — |
| Research Site 41 | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04720534, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 24, 2026 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04720534 live on ClinicalTrials.gov.