A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
Public ClinicalTrials.gov record NCT04729114. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 1, Open-Label, Multicenter Study of Intramuscular PRL-02 Depot in Patients With Advanced Prostate Cancer
Study identification
- NCT ID
- NCT04729114
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Astellas Pharma Global Development, Inc.
- Industry
- Enrollment
- 174 participants
Conditions and interventions
Conditions
Interventions
- PRL-02 injection Drug
- dexamethasone Drug
- enzalutamide Drug
- prednisone Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 13, 2021
- Primary completion
- May 30, 2029
- Completion
- May 30, 2029
- Last update posted
- Feb 3, 2026
2021 – 2029
United States locations
- U.S. sites
- 24
- U.S. states
- 17
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Urology Specialists | Tucson | Arizona | 85715 | Withdrawn |
| Los Angeles Cancer Network | Anaheim | California | 92801 | Recruiting |
| Providence Medical Group Oncology Santa Rosa | Santa Rosa | California | 95403 | Recruiting |
| Florida Urology Partners | Tampa | Florida | 33609 | Withdrawn |
| Fort Wayne Medical Oncology and Hematology, Inc. | Fort Wayne | Indiana | 46804 | Withdrawn |
| First Urology | Jeffersonville | Indiana | 47130 | Recruiting |
| Wichita Urology Group | Wichita | Kansas | 67226 | Recruiting |
| National Cancer Institute | Bethesda | Maryland | 20892 | Withdrawn |
| Chesapeake Urology | Towson | Maryland | 21204 | Recruiting |
| XCancer Center Omaha/Urology Cancer Center | Omaha | Nebraska | 68130 | Completed |
| Garden Sate Urology | Morristown | New Jersey | 07960 | Withdrawn |
| New Mexico Oncology Hematology Consultants Ltd | Albuquerque | New Mexico | 87109 | Recruiting |
| Duke Cancer Center | Durham | North Carolina | 27710 | Recruiting |
| Helios Clinical Research, LLC | Middleburg Heights | Ohio | 44130 | Withdrawn |
| Toledo Clinical Cancer Center | Toledo | Ohio | 43623 | Withdrawn |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Urology Associates PC | Nashville | Tennessee | 37209 | Recruiting |
| Urology Clinics of North Texas | Dallas | Texas | 75231 | Recruiting |
| Houston Metro Urology | Houston | Texas | 77027 | Recruiting |
| Oncology Consultants | Houston | Texas | 77030 | Withdrawn |
| Urology San Antonio | San Antonio | Texas | 78229 | Withdrawn |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | Recruiting |
| Northwest Medical Specialties | Tacoma | Washington | 98405 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04729114, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2026 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04729114 live on ClinicalTrials.gov.